Host-parasite co-metabolic activation of antitrypanosomal aminomethyl-benzoxaboroles

Recent development of benzoxaborole-based chemistry gave rise to a collection of compounds with great potential in targeting diverse infectious diseases, including human African Trypanosomiasis (HAT), a devastating neglected tropical disease. However, further medicinal development is largely restric...

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Detalles Bibliográficos
Autores principales: Zhang, Ning, Zoltner, Martin, Leung, Ka-Fai, Scullion, Paul, Hutchinson, Sebastian, del Pino, Ricardo C., Vincent, Isabel M., Zhang, Yong-Kang, Freund, Yvonne R., Alley, Michael R. K., Jacobs, Robert T., Read, Kevin D., Barrett, Michael P., Horn, David, Field, Mark C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5823473/
https://www.ncbi.nlm.nih.gov/pubmed/29425238
http://dx.doi.org/10.1371/journal.ppat.1006850

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