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Mucinous carcinoma of the gallbladder with signet ring cells

Most gallbladder carcinomas are adenocarcinomas, of which mucinous carcinoma (MC) is a rare pathologic subtype. Signet ring cells are seldom found in MCs. We report an extremely rare case of gallbladder MC with signet ring cells. This is the first radiological case report about this rare type of his...

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Autores principales: Fukuda, Takeshi, Sakimoto, Yoshihiro, Narita, Kenichi, Ariizumi, Mitsuko, Aizawa, Yoshio, Fukuda, Kunihiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5823477/
https://www.ncbi.nlm.nih.gov/pubmed/29484053
http://dx.doi.org/10.1016/j.radcr.2017.06.016
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author Fukuda, Takeshi
Sakimoto, Yoshihiro
Narita, Kenichi
Ariizumi, Mitsuko
Aizawa, Yoshio
Fukuda, Kunihiko
author_facet Fukuda, Takeshi
Sakimoto, Yoshihiro
Narita, Kenichi
Ariizumi, Mitsuko
Aizawa, Yoshio
Fukuda, Kunihiko
author_sort Fukuda, Takeshi
collection PubMed
description Most gallbladder carcinomas are adenocarcinomas, of which mucinous carcinoma (MC) is a rare pathologic subtype. Signet ring cells are seldom found in MCs. We report an extremely rare case of gallbladder MC with signet ring cells. This is the first radiological case report about this rare type of histologic entity with detailed discussion of imaging findings in the English literature. In addition to the features of MC, linitis plastica-like invasion, which is the key feature of signet ring cells, was confirmed by both imaging and histopathologic analysis. Furthermore, radiologists should know how the imaging findings of MC differ from those of other major subtypes of adenocarcinoma, as there is a risk of delays in diagnosis and underestimation of tumor spread.
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spelling pubmed-58234772018-02-26 Mucinous carcinoma of the gallbladder with signet ring cells Fukuda, Takeshi Sakimoto, Yoshihiro Narita, Kenichi Ariizumi, Mitsuko Aizawa, Yoshio Fukuda, Kunihiko Radiol Case Rep Gastrointestinal Most gallbladder carcinomas are adenocarcinomas, of which mucinous carcinoma (MC) is a rare pathologic subtype. Signet ring cells are seldom found in MCs. We report an extremely rare case of gallbladder MC with signet ring cells. This is the first radiological case report about this rare type of histologic entity with detailed discussion of imaging findings in the English literature. In addition to the features of MC, linitis plastica-like invasion, which is the key feature of signet ring cells, was confirmed by both imaging and histopathologic analysis. Furthermore, radiologists should know how the imaging findings of MC differ from those of other major subtypes of adenocarcinoma, as there is a risk of delays in diagnosis and underestimation of tumor spread. Elsevier 2017-08-12 /pmc/articles/PMC5823477/ /pubmed/29484053 http://dx.doi.org/10.1016/j.radcr.2017.06.016 Text en © 2017 The Authors http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Gastrointestinal
Fukuda, Takeshi
Sakimoto, Yoshihiro
Narita, Kenichi
Ariizumi, Mitsuko
Aizawa, Yoshio
Fukuda, Kunihiko
Mucinous carcinoma of the gallbladder with signet ring cells
title Mucinous carcinoma of the gallbladder with signet ring cells
title_full Mucinous carcinoma of the gallbladder with signet ring cells
title_fullStr Mucinous carcinoma of the gallbladder with signet ring cells
title_full_unstemmed Mucinous carcinoma of the gallbladder with signet ring cells
title_short Mucinous carcinoma of the gallbladder with signet ring cells
title_sort mucinous carcinoma of the gallbladder with signet ring cells
topic Gastrointestinal
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5823477/
https://www.ncbi.nlm.nih.gov/pubmed/29484053
http://dx.doi.org/10.1016/j.radcr.2017.06.016
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