Expression of the mRNA stability regulator Tristetraprolin is required for lactation maintenance in the mouse mammary gland

Tristetraprolin (TTP), an mRNA-binding protein that negatively controls levels of inflammatory factors, is highly expressed in the lactating mouse mammary gland. To determine the biological relevance of this expression profile, we developed bi-transgenic mice in which this protein is specifically do...

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Detalles Bibliográficos
Autores principales: Goddio, María Victoria, Gattelli, Albana, Tocci, Johanna M., Cuervo, Lourdes Pérez, Stedile, Micaela, Stumpo, Deborah J., Hynes, Nancy E., Blackshear, Perry J., Meiss, Roberto P., Kordon, Edith C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Research Paper: Autophagy and Cell Death
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5823555/
https://www.ncbi.nlm.nih.gov/pubmed/29492194
http://dx.doi.org/10.18632/oncotarget.23904

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