Cargando…

Genetic alterations in main candidate genes during melanoma progression

Cutaneous melanoma is a common and aggressive human skin cancers. Much is actually known about the molecular mechanisms underlying melanoma pathogenesis. The aim of the study was to evaluate any possible correlation between mutations in main growth-controlling genes (BRAF, NRAS, CDKN2A) and copy num...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sini, Maria Cristina, Doneddu, Valentina, Paliogiannis, Panagiotis, Casula, Milena, Colombino, Maria, Manca, Antonella, Botti, Gerardo, Ascierto, Paolo A., Lissia, Amelia, Cossu, Antonio, Palmieri, Giuseppe
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2018
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5823576/ https://www.ncbi.nlm.nih.gov/pubmed/29492214 http://dx.doi.org/10.18632/oncotarget.23989

Ejemplares similares

Mutational concordance between primary and metastatic melanoma: a next-generation sequencing approach
por: Manca, Antonella, et al.
Publicado: (2019)

Discrepant alterations in main candidate genes among multiple primary melanomas
por: Colombino, Maria, et al.
Publicado: (2014)

Comparison of BRAF Mutation Screening Strategies in a Large Real-Life Series of Advanced Melanoma Patients
por: Colombino, Maria, et al.
Publicado: (2020)

Assessment of germline and somatic alterations in main candidate genes among patients with multiple primary melanoma
por: Colombino, Maria, et al.
Publicado: (2014)

Are Molecular Alterations Linked to Genetic Instability Worth to Be Included as Biomarkers for Directing or Excluding Melanoma Patients to Immunotherapy?
por: Palmieri, Giuseppe, et al.
Publicado: (2021)

BRAF Mutations and Dysregulation of the MAP Kinase Pathway Associated to Sinonasal Mucosal Melanomas
por: Colombino, Maria, et al.
Publicado: (2019)

Dietary compounds and cutaneous malignant melanoma: recent advances from a biological perspective
por: Ombra, Maria Neve, et al.
Publicado: (2019)

Activating PIK3CA mutations coexist with BRAF or NRAS mutations in a limited fraction of melanomas
por: Manca, Antonella, et al.
Publicado: (2015)

EGFR, KRAS, BRAF, ALK, and cMET genetic alterations in 1440 Sardinian patients with lung adenocarcinoma
por: Colombino, Maria, et al.
Publicado: (2019)

Germline and somatic mutations in patients with multiple primary melanomas: a next generation sequencing study
por: Casula, Milena, et al.
Publicado: (2019)

KIT and PDGFRa mutational patterns in Sardinian patients with gastrointestinal stromal tumors
por: Palomba, Grazia, et al.
Publicado: (2020)

Multiple Molecular Pathways in Melanomagenesis: Characterization of Therapeutic Targets
por: Palmieri, Giuseppe, et al.
Publicado: (2015)

Global prognostic impact of driver genetic alterations in patients with lung adenocarcinoma: a real-life study
por: Paliogiannis, Panagiotis, et al.
Publicado: (2022)

Primary Dermal Melanoma in a Patient with a History of Multiple Malignancies: A Case Report with Molecular Characterization
por: Sini, Germana, et al.
Publicado: (2013)

Vitamin D status and risk for malignant cutaneous melanoma: recent advances
por: Ombra, Maria N., et al.
Publicado: (2017)

Primary Melanoma of the Lung: A Systematic Review
por: Paliogiannis, Panagiotis, et al.
Publicado: (2020)

Comparison between Three Different Techniques for the Detection of EGFR Mutations in Liquid Biopsies of Patients with Advanced Stage Lung Adenocarcinoma
por: Casula, Milena, et al.
Publicado: (2023)

Main roads to melanoma
por: Palmieri, Giuseppe, et al.
Publicado: (2009)

Definition of the role of chromosome 9p21 in sporadic melanoma through genetic analysis of primary tumours and their metastases
por: Palmieri, G, et al.
Publicado: (2000)

Heterogeneous distribution of BRAF/NRAS mutations among Italian patients with advanced melanoma
por: Colombino, Maria, et al.
Publicado: (2013)

Quality assessment of a clinical next-generation sequencing melanoma panel within the Italian Melanoma Intergroup (IMI)
por: Vanni, Irene, et al.
Publicado: (2020)

Molecular Pathways in Melanomagenesis: What We Learned from Next-Generation Sequencing Approaches
por: Palmieri, Giuseppe, et al.
Publicado: (2018)

Issues affecting molecular staging in the management of patients with melanoma
por: Palmieri, G, et al.
Publicado: (2007)

Genetic instability and increased mutational load: which diagnostic tool best direct patients with cancer to immunotherapy?
por: Palmieri, Giuseppe, et al.
Publicado: (2017)

Mammary-like adenocarcinoma of the vulva: a rare case report with next generation sequencing
por: Lobrano, Renato, et al.
Publicado: (2023)

Molecular analysis of appendiceal mucinous cystadenoma and rectal adenocarcinoma in a patient with urothelial carcinoma: a case report
por: Pulighe, Fabio, et al.
Publicado: (2013)

Current Trends in Mucosal Melanomas: An Overview
por: Santeufemia, Davide Adriano, et al.
Publicado: (2023)

Molecular Epidemiology of the Main Druggable Genetic Alterations in Non-Small Cell Lung Cancer
por: Fois, Sara S., et al.
Publicado: (2021)

Prognostic impact of KRAS, NRAS, BRAF, and PIK3CA mutations in primary colorectal carcinomas: a population-based study
por: Palomba, Grazia, et al.
Publicado: (2016)

Role of key-regulator genes in melanoma susceptibility and pathogenesis among patients from South Italy
por: Casula, Milena, et al.
Publicado: (2009)

Liquid Biopsy in the Oncological Management of a Histologically Undiagnosed Lung Carcinoma: A Case Report
por: Fadda, Giovanni M., et al.
Publicado: (2022)

Perivascular Epithelioid Cell Tumors (PEComas) of the Orbit
por: Paliogiannis, Panagiotis, et al.
Publicado: (2017)

NGS-Based Analysis of Atypical Deep Penetrating Nevi
por: Manca, Antonella, et al.
Publicado: (2021)

Impact of tissue type and content of neoplastic cells of samples on the quality of epidermal growth factor receptor mutation analysis among patients with lung adenocarcinoma
por: PALIOGIANNIS, PANAGIOTIS, et al.
Publicado: (2015)

COX-2 expression positively correlates with PD-L1 expression in human melanoma cells
por: Botti, Gerardo, et al.
Publicado: (2017)

KRAS mutational concordance between primary and metastatic colorectal adenocarcinoma
por: PALIOGIANNIS, PANAGIOTIS, et al.
Publicado: (2014)

Phase III randomized study of fotemustine and dacarbazine versus dacarbazine with or without interferon-α in advanced malignant melanoma
por: Daponte, Antonio, et al.
Publicado: (2013)

Immune Checkpoint Inhibitors in Melanoma and HIV Infection
por: Marra, Antonio, et al.
Publicado: (2017)

Circulating Tumor DNA Testing Opens New Perspectives in Melanoma Management
por: Sacco, Alessandra, et al.
Publicado: (2020)

Role of the EGF +61A>G polymorphism in melanoma pathogenesis: an experience on a large series of Italian cases and controls
por: Casula, Milena, et al.
Publicado: (2009)

Cannot write session to /tmp/vufind_sessions/sess_bendfuqbqm6pam81o6luc63c29