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The mutational landscape of MYCN, Lin28b and ALK(F1174L) driven murine neuroblastoma mimics human disease

Genetically engineered mouse models have proven to be essential tools for unraveling fundamental aspects of cancer biology and for testing novel therapeutic strategies. To optimally serve these goals, it is essential that the mouse model faithfully recapitulates the human disease. Recently, novel mo...

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Detalles Bibliográficos
Autores principales: De Wilde, Bram, Beckers, Anneleen, Lindner, Sven, Kristina, Althoff, De Preter, Katleen, Depuydt, Pauline, Mestdagh, Pieter, Sante, Tom, Lefever, Steve, Hertwig, Falk, Peng, Zhiyu, Shi, Le-Ming, Lee, Sangkyun, Vandermarliere, Elien, Martens, Lennart, Menten, Björn, Schramm, Alexander, Fischer, Matthias, Schulte, Johannes, Vandesompele, Jo, Speleman, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5823580/
https://www.ncbi.nlm.nih.gov/pubmed/29492199
http://dx.doi.org/10.18632/oncotarget.23614

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