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Proteomic analysis of chicken embryo fibroblast cells infected with recombinant H5N1 avian influenza viruses with and without NS1 eIF4GI binding domain

Non-structural 1 (NS1) protein is a key virulence factor that regulates replication of influenza virus. A recombinant H5N1 virus lacking the eIF4GI-binding domain of NS1 (rNS1-SD30) exhibits significantly lower pathogenicity than H5N1 virus with an intact eIF4GI-binding domain (rNS1-wt). To further...

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Detalles Bibliográficos
Autores principales:	Guo, Kelei, Lin, Xian, Li, Yongtao, Qian, Wei, Zou, Zhong, Chen, Huanchun, Zhou, Hongbo, Jin, Meilin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2017
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5823584/ https://www.ncbi.nlm.nih.gov/pubmed/29492200 http://dx.doi.org/10.18632/oncotarget.23615

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