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Incidence and risk of hepatic toxicities associated with anaplastic lymphoma kinase inhibitors in the treatment of non-small-cell lung cancer: a systematic review and meta-analysis

BACKGROUND: Two anaplastic lymphoma kinase (ALK)-tyrosine kinase inhibitors (-TKIs) have been approved for the treatment of patients with ALK-rearranged (ALK-positive) advanced non-small cell lung cancer (NSCLC). Severe hepatotoxicity has been observed in several clinical studies. We aim to assess t...

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Detalles Bibliográficos
Autores principales:	Liu, Bing, Yuan, Maoxi, Sun, Yi, Cheng, Ziming, Zhang, Zaiyong, Hou, Shizheng, Wang, Xiangdong, Liu, Jingfeng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2017
Materias:	Meta-Analysis
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5823621/ https://www.ncbi.nlm.nih.gov/pubmed/29507704 http://dx.doi.org/10.18632/oncotarget.23840

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