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Copper/MYC/CTR1 interplay: a dangerous relationship in hepatocellular carcinoma

Free serum copper correlates with tumor incidence and progression of human cancers, including hepatocellular carcinoma (HCC). Copper extracellular uptake is provided by the transporter CTR1, whose expression is regulated to avoid excessive intracellular copper entry. Inadequate copper serum concentr...

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Detalles Bibliográficos
Autores principales: Porcu, Cristiana, Antonucci, Laura, Barbaro, Barbara, Illi, Barbara, Nasi, Sergio, Martini, Maurizio, Licata, Anna, Miele, Luca, Grieco, Antonio, Balsano, Clara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5823635/
https://www.ncbi.nlm.nih.gov/pubmed/29507693
http://dx.doi.org/10.18632/oncotarget.24282