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High GSTP1 inhibits cell proliferation by reducing Akt phosphorylation and is associated with a better prognosis in hepatocellular carcinoma
Glutathione S-transferase (GST) family members promote carcinogenesis and cancer progression. We assessed GST pi 1 (GSTP1) mRNA and protein levels in hepatocellular carcinoma (HCC) using genome databases and tissue microarray (TMA) technology. We found that in cancerous tissues, GSTP1 mRNA was down-...
Autores principales: | Liu, Xiaojia, Tan, Ning, Liao, Hongtao, Pan, Guangdong, Xu, Qing, Zhu, Rong, Zou, Liping, He, Songqing, Zhu, Hongguang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5823662/ https://www.ncbi.nlm.nih.gov/pubmed/29507666 http://dx.doi.org/10.18632/oncotarget.23420 |
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