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Mitochondrial oxidative stress activates COX-2/mPGES-1/PGE2 cascade induced by albumin in renal proximal tubular cells
COX-2/mPGES-1/PGE2 cascade is of importance in the pathogenesis of kidney injury. Meanwhile, recent studies documented a detrimental role of mitochondrial oxidative stress in kidney diseases. The present study was undertaken to investigate the role of mitochondrial oxidative stress in albumin-induce...
Autores principales: | Zhuang, Yibo, Wang, Chenhu, Wu, Chunfeng, Ding, Dan, Zhao, Fei, Hu, Caiyu, Gong, Wei, Ding, Guixia, Zhang, Yue, Chen, Lihong, Yang, Guangrui, Zhu, Chunhua, Zhang, Aihua, Jia, Zhanjun, Huang, Songming |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5823666/ https://www.ncbi.nlm.nih.gov/pubmed/29507686 http://dx.doi.org/10.18632/oncotarget.24187 |
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