Cargando…

Teneligliptin enhances the beneficial effects of GLP-1 in endothelial cells exposed to hyperglycemic conditions

High-glucose-induced oxidative stress contributes to cardiovascular endothelial damage in diabetes. Glucagon-like peptide 1 (GLP-1) is beneficial to endothelial cells, but its effects are diminished when cells are continuously exposed to high glucose. Teneligliptin is a dipeptidyl peptidase-4 (DPP-4...

Descripción completa

Detalles Bibliográficos
Autores principales:	De Nigris, Valeria, Prattichizzo, Francesco, Mancuso, Elettra, Spiga, Rosangela, Pujadas, Gemma, Ceriello, Antonio
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2017
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5823668/ https://www.ncbi.nlm.nih.gov/pubmed/29507662 http://dx.doi.org/10.18632/oncotarget.22849

Ejemplares similares

The dipeptidyl peptidase-4 (DPP-4) inhibitor teneligliptin functions as antioxidant on human endothelial cells exposed to chronic hyperglycemia and metabolic high-glucose memory
por: Pujadas, Gemma, et al.
Publicado: (2016)

DPP-4 Inhibitors Have Different Effects on Endothelial Low-Grade Inflammation and on the M1-M2 Macrophage Polarization Under Hyperglycemic Conditions
por: De Nigris, Valeria, et al.
Publicado: (2021)

The Unique Pharmacological and Pharmacokinetic Profile of Teneligliptin: Implications for Clinical Practice
por: Ceriello, Antonio, et al.
Publicado: (2019)

The protective effect of the Mediterranean diet on endothelial resistance to GLP-1 in type 2 diabetes: a preliminary report
por: Ceriello, Antonio, et al.
Publicado: (2014)

Short-term sustained hyperglycaemia fosters an archetypal senescence-associated secretory phenotype in endothelial cells and macrophages
por: Prattichizzo, Francesco, et al.
Publicado: (2017)

GLP-1 reduces metalloproteinase-9 induced by both hyperglycemia and hypoglycemia in type 1 diabetes. The possible role of oxidative stress
por: Ceriello, Antonio, et al.
Publicado: (2015)

Short-term high glucose exposure impairs insulin signaling in endothelial cells
por: De Nigris, Valeria, et al.
Publicado: (2015)

Extracellular microRNAs and endothelial hyperglycaemic memory: a therapeutic opportunity?
por: Prattichizzo, F., et al.
Publicado: (2016)

Oscillating glucose induces microRNA-185 and impairs an efficient antioxidant response in human endothelial cells
por: La Sala, Lucia, et al.
Publicado: (2016)

The “Metabolic Memory” Theory and the Early Treatment of Hyperglycemia in Prevention of Diabetic Complications
por: Testa, Roberto, et al.
Publicado: (2017)

“Inflammaging” as a Druggable Target: A Senescence-Associated Secretory Phenotype—Centered View of Type 2 Diabetes
por: Prattichizzo, Francesco, et al.
Publicado: (2016)

Efficacy and safety of teneligliptin
por: Singh, Awadhesh Kumar
Publicado: (2017)

Extracellular vesicle-shuttled miRNAs: a critical appraisal of their potential as nano-diagnostics and nano-therapeutics in type 2 diabetes mellitus and its cardiovascular complications
por: Prattichizzo, Francesco, et al.
Publicado: (2021)

Plasma kisspeptin levels are associated with insulin secretion in nondiabetic individuals
por: Andreozzi, Francesco, et al.
Publicado: (2017)

Teneligliptin protects against ischemia/reperfusion-induced endothelial permeability in vivo and in vitro
por: Zhang, Lei, et al.
Publicado: (2020)

Vitamin C further improves the protective effect of GLP-1 on the ischemia-reperfusion-like effect induced by hyperglycemia post-hypoglycemia in type 1 diabetes
por: Ceriello, Antonio, et al.
Publicado: (2013)

Targeting redox imbalance in neurodegeneration: characterizing the role of GLP-1 receptor agonists
por: Ghosh, Puja, et al.
Publicado: (2023)

Extracellular vesicles circulating in young organisms promote healthy longevity
por: Prattichizzo, Francesco, et al.
Publicado: (2019)

Pharmacological management of COVID-19 in type 2 diabetes
por: Ceriello, Antonio, et al.
Publicado: (2021)

Variability of risk factors and diabetes complications
por: Ceriello, Antonio, et al.
Publicado: (2021)

Teneligliptin in management of type 2 diabetes mellitus
por: Sharma, Surendra Kumar, et al.
Publicado: (2016)

Teneligliptin and “Thorough QTc study”: thorough enough?
por: Ghosal, Samit
Publicado: (2019)

Insulin-like growth factor-1 is a negative modulator of glucagon secretion
por: Mancuso, Elettra, et al.
Publicado: (2017)

Proinflammatory cytokines trigger biochemical and neurochemical changes in mouse retinal explants exposed to hyperglycemic conditions
por: Shivashankar, Gaganashree, et al.
Publicado: (2020)

GIP Does Not Potentiate the Antidiabetic Effects of GLP-1 in Hyperglycemic Patients With Type 2 Diabetes
por: Mentis, Nikolaos, et al.
Publicado: (2011)

Study on the Hyperglycemic Effect of GLP-1 in Spinibarbus denticulatus by Oral Administration and Intraperitoneal Injection Methods
por: Luo, Wei, et al.
Publicado: (2023)

Teneligliptin-induced hair loss: A case report
por: Agrawal, Prabhat K., et al.
Publicado: (2020)

Exanthematous Drug Eruption as a Side Effect of Teneligliptin
por: Sunil, Krupa A., et al.
Publicado: (2021)

Changes in cultured endothelial cell glycosaminoglycans under hyperglycemic conditions and the effect of insulin and heparin
por: Han, Juying, et al.
Publicado: (2009)

Impact of cigarette smoke extract and hyperglycemic conditions on blood–brain barrier endothelial cells
por: Prasad, Shikha, et al.
Publicado: (2015)

The effects of humic water on endothelial cells under hyperglycemic conditions: inflammation-associated parameters
por: Szot, Katarzyna, et al.
Publicado: (2019)

Effects of teneligliptin on PDMPs and PAI-1 in patients with diabetes on hemodialysis
por: Okuda, Yoshinori, et al.
Publicado: (2016)

Therapeutic Effect of Teneligliptin in Drug-Induced Nephrotoxicity: An In-Vitro Study
por: Becerir, Tülay, et al.
Publicado: (2022)

The polymorphism rs35767 at IGF1 locus is associated with serum urate levels
por: Mannino, Gaia C., et al.
Publicado: (2018)

Teneligliptin, a DPP-4 Inhibitor, Improves Vascular Endothelial Function via Divergent Actions Including Changes in Circulating Endothelial Progenitor Cells
por: Akashi, Naoyuki, et al.
Publicado: (2023)

Concurrent Use of Teneligliptin and Canagliflozin Improves Glycemic Control with Beneficial Effects on Plasma Glucagon and Glucagon-Like Peptide-1: A Single-Arm Study
por: Noda, Tomoho, et al.
Publicado: (2019)

Glucagon-Like Peptide 1 Reduces Endothelial Dysfunction, Inflammation, and Oxidative Stress Induced by Both Hyperglycemia and Hypoglycemia in Type 1 Diabetes
por: Ceriello, Antonio, et al.
Publicado: (2013)

O-GlcNAcylation of GLI Transcription Factors in Hyperglycemic Conditions Augments Hedgehog activity: Hyperglycemic conditions upregulate GLI activity
por: Das, Shamik, et al.
Publicado: (2018)

Mesenchymal Stem Cells Potentiate the Vasculogenic Capacity of Endothelial Colony-Forming Cells under Hyperglycemic Conditions
por: Lee, Hyunsook, et al.
Publicado: (2022)

Hyperglycemic conditions induce rapid cell dysfunction-promoting transcriptional alterations in human aortic endothelial cells
por: Bayaraa, Odmaa, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_t94qq4kvvp4jotvf3o9iv6ikij