Cargando…

Human perforin gene variation is geographically distributed

BACKGROUND: Deleterious mutations in PRF1 result in lethal, childhood disease, familial hemophagocytic lymphohistiocytosis type 2 (FHL 2). However, not all mutations in PRF1 are deleterious and result in FHL 2. Currently, these nondeleterious mutations are being investigated in the onset of numerous...

Descripción completa

Detalles Bibliográficos
Autores principales:	Willenbring, Robin C., Ikeda, Yasuhiro, Pease, Larry R., Johnson, Aaron J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2017
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5823683/ https://www.ncbi.nlm.nih.gov/pubmed/29216683 http://dx.doi.org/10.1002/mgg3.344

Ejemplares similares

Finding a Balance between Protection and Pathology: The Dual Role of Perforin in Human Disease
por: Willenbring, Robin C., et al.
Publicado: (2017)

Modulatory effects of perforin gene dosage on pathogen-associated blood-brain barrier (BBB) disruption
por: Willenbring, Robin C., et al.
Publicado: (2016)

Perforin Competent CD8 T Cells Are Sufficient to Cause Immune-Mediated Blood-Brain Barrier Disruption
por: Johnson, Holly L., et al.
Publicado: (2014)

Perforin Gene Transfer Into Hematopoietic Stem Cells Improves Immune Dysregulation in Murine Models of Perforin Deficiency
por: Carmo, Marlene, et al.
Publicado: (2015)

Perforin gene mutations in 77 Chinese patients with lymphomas
por: Ding, Qi, et al.
Publicado: (2013)

The combination of the prodrugs perforin-CEBPD and perforin-granzyme B efficiently enhances the activation of caspase signaling and kills prostate cancer
por: Chuang, C-H, et al.
Publicado: (2014)

Perforin and hematological cancer
por: Covas, Dimas Tadeu
Publicado: (2011)

Human Perforin Employs Different Avenues to Damage Membranes
por: Praper, Tilen, et al.
Publicado: (2011)

Analysis of the -398C/T polymorphism in the perforin gene in oncohematological patients
por: Garcia, Fernanda Bernadelli, et al.
Publicado: (2011)

The pore conformation of lymphocyte perforin
por: Ivanova, Marina E., et al.
Publicado: (2022)

Molecular study of the perforin gene in familial hematological malignancies
por: El Abed, Rim, et al.
Publicado: (2011)

Perforin expression in lymphocytes infiltrated to human colorectal cancer.
por: Nakanishi, H., et al.
Publicado: (1991)

Human perforin mutations and susceptibility to multiple primary cancers
por: Trapani, Joseph A., et al.
Publicado: (2013)

Adenosine leakage from perforin-burst extracellular vesicles inhibits perforin secretion by cytotoxic T-lymphocytes
por: Tadokoro, Hiroko, et al.
Publicado: (2020)

Expression of perforin and serine esterases by human gamma/delta T cells
Publicado: (1991)

Benzenesulphonamide inhibitors of the cytolytic protein perforin
por: Spicer, Julie A., et al.
Publicado: (2017)

Perforin: an important player in immune response
por: Osińska, Iwona, et al.
Publicado: (2014)

Perforin-Like Proteins of Apicomplexan Parasites
por: Sassmannshausen, Juliane, et al.
Publicado: (2020)

Perforin and resistance to SARS coronavirus 2
por: Cunningham, Louise, et al.
Publicado: (2020)

Lipid specificity of the immune effector perforin
por: Hodel, Adrian W., et al.
Publicado: (2020)

Editorial: Perforins and Cholesterol-Dependent Cytolysins in Immunity and Pathogenesis
por: Munson, George P., et al.
Publicado: (2022)

Evolution and Expression of the Membrane Attack Complex and Perforin Gene Family in the Poaceae
por: Yu, Lujun, et al.
Publicado: (2020)

Correction: Perforin Is Detrimental to Controlling C. muridarum Replication In Vitro, but Not In Vivo
por: Johnson, Raymond M., et al.
Publicado: (2013)

Perforin Is Detrimental to Controllinγ C. muridarum Replication In Vitro, but Not In Vivo
por: Johnson, Raymond M., et al.
Publicado: (2013)

Cytolytic Perforin as an Adjuvant to Enhance the Immunogenicity of DNA Vaccines
por: Shrestha, Ashish C., et al.
Publicado: (2019)

Substituted arylsulphonamides as inhibitors of perforin-mediated lysis
por: Spicer, Julie A., et al.
Publicado: (2017)

Perforin deficiency attenuates collagen-induced arthritis
por: Bauer, Kristin, et al.
Publicado: (2005)

Decreased tumor surveillance in perforin-deficient mice
Publicado: (1996)

Diarylthiophenes as inhibitors of the pore-forming protein perforin
por: Miller, Christian K., et al.
Publicado: (2016)

Perforins Expression by Cutaneous Gamma Delta T Cells
por: O'Neill, Katelyn, et al.
Publicado: (2020)

Large-Scale Geographic Variation in Distribution and Abundance of Australian Deep-Water Kelp Forests
por: Marzinelli, Ezequiel M., et al.
Publicado: (2015)

Expression of Perforin Gene for Early Development of Nephrons in Olive Flounder (Paralichthys olivaceus)
por: Yang, Hyun, et al.
Publicado: (2013)

Perforin-Mediated Cytotoxicity Is Critical for Surveillance of Spontaneous Lymphoma
por: Smyth, Mark J., et al.
Publicado: (2000)

Perforin Rapidly Induces Plasma Membrane Phospholipid Flip-Flop
por: Metkar, Sunil S., et al.
Publicado: (2011)

Geographical Genomics of Human Leukocyte Gene Expression Variation in Southern Morocco
por: Idaghdour, Youssef, et al.
Publicado: (2009)

Perforin enhances the granulysin-induced lysis of Listeria innocua in human dendritic cells
por: Walch, Michael, et al.
Publicado: (2007)

Geographic variations of the prevalence and distribution of COPD phenotypes in Spain: “the ESPIRAL-ES study”
por: Alcázar-Navarrete, Bernardino, et al.
Publicado: (2018)

Geographic variation in incubation behavior of a widely distributed passerine bird
por: Rohwer, Vanya G., et al.
Publicado: (2019)

Perforin Acts as an Immune Regulator to Prevent the Progression of NAFLD
por: Wang, Qian, et al.
Publicado: (2020)

Perforin and serine esterase gene expression in stimulated human T cells. Kinetics, mitogen requirements, and effects of cyclosporin A
Publicado: (1989)

Cannot write session to /tmp/vufind_sessions/sess_6v0casvh448mq4l6r344ekkjf9