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MLK3 phosphorylation by ERK1/2 is required for oxidative stress-induced invasion of colorectal cancer cells

Mixed lineage kinase 3 (MLK3) functions in migration and/or invasion of several human cancers; however, the role of MLK3 in colorectal cancer (CRC) invasion is unknown. MLK3 is a mitogen-activated protein kinase (MAPK) kinase kinase (MAP3K) which activates MAPK pathways through either kinase-depende...

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Detalles Bibliográficos
Autores principales:	Schroyer, April L., Stimes, Nicholas W., Abi Saab, Widian F., Chadee, Deborah N.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5823719/ https://www.ncbi.nlm.nih.gov/pubmed/29084209 http://dx.doi.org/10.1038/onc.2017.396

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