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Development of a Gustatory Function Test for Clinical Application in Korean Subjects

PURPOSE: To obtain validated clinical values suitable for developing a gustatory function test, including umami taste, in a Korean population. MATERIALS AND METHODS: The investigation involved 297 participants with self-reported normal sense of taste and smell. Liquid solutions were used for the ass...

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Autores principales: Hwang, Chi Sang, Kim, Jin Won, Al Sharhan, Salma Saud, Kim, Jin Woong, Cho, Hyung-Ju, Yoon, Joo-Heon, Kim, Chang-Hoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Yonsei University College of Medicine 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5823837/
https://www.ncbi.nlm.nih.gov/pubmed/29436203
http://dx.doi.org/10.3349/ymj.2018.59.2.325
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author Hwang, Chi Sang
Kim, Jin Won
Al Sharhan, Salma Saud
Kim, Jin Woong
Cho, Hyung-Ju
Yoon, Joo-Heon
Kim, Chang-Hoon
author_facet Hwang, Chi Sang
Kim, Jin Won
Al Sharhan, Salma Saud
Kim, Jin Woong
Cho, Hyung-Ju
Yoon, Joo-Heon
Kim, Chang-Hoon
author_sort Hwang, Chi Sang
collection PubMed
description PURPOSE: To obtain validated clinical values suitable for developing a gustatory function test, including umami taste, in a Korean population. MATERIALS AND METHODS: The investigation involved 297 participants with self-reported normal sense of taste and smell. Liquid solutions were used for the assessment of gustatory function. The test consisted of 30 taste solutions [six concentrations of five tastants (sweet, bitter, salty, sour, and umami)]. For evaluation of overall gustatory function, the number of detected or correctly recognized taste thresholds was combined to form a “taste score.” RESULTS: Mean values of each detection and recognition threshold for the five tastes in men were consistently lower than those of women. The 10th percentile of taste score for recognition was used as the cut-off value for distinguishing normogeusia from hypogeusia. In subgroup analysis, total taste score from recognition thresholds revealed a significant negative correlation with age, indicating lower scores for increasing age. Taste score for non-smokers was significantly higher than that of smokers, in terms of detection and recognition of taste sensitivities. CONCLUSION: This gustatory function test was easy to perform, affordable, and time-saving, with the capacity to self-produce and obtain reliable data. Gustatory function was more sensitive in young people, women, and non-smokers.
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spelling pubmed-58238372018-03-01 Development of a Gustatory Function Test for Clinical Application in Korean Subjects Hwang, Chi Sang Kim, Jin Won Al Sharhan, Salma Saud Kim, Jin Woong Cho, Hyung-Ju Yoon, Joo-Heon Kim, Chang-Hoon Yonsei Med J Original Article PURPOSE: To obtain validated clinical values suitable for developing a gustatory function test, including umami taste, in a Korean population. MATERIALS AND METHODS: The investigation involved 297 participants with self-reported normal sense of taste and smell. Liquid solutions were used for the assessment of gustatory function. The test consisted of 30 taste solutions [six concentrations of five tastants (sweet, bitter, salty, sour, and umami)]. For evaluation of overall gustatory function, the number of detected or correctly recognized taste thresholds was combined to form a “taste score.” RESULTS: Mean values of each detection and recognition threshold for the five tastes in men were consistently lower than those of women. The 10th percentile of taste score for recognition was used as the cut-off value for distinguishing normogeusia from hypogeusia. In subgroup analysis, total taste score from recognition thresholds revealed a significant negative correlation with age, indicating lower scores for increasing age. Taste score for non-smokers was significantly higher than that of smokers, in terms of detection and recognition of taste sensitivities. CONCLUSION: This gustatory function test was easy to perform, affordable, and time-saving, with the capacity to self-produce and obtain reliable data. Gustatory function was more sensitive in young people, women, and non-smokers. Yonsei University College of Medicine 2018-03-01 2017-02-05 /pmc/articles/PMC5823837/ /pubmed/29436203 http://dx.doi.org/10.3349/ymj.2018.59.2.325 Text en © Copyright: Yonsei University College of Medicine 2018 http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Hwang, Chi Sang
Kim, Jin Won
Al Sharhan, Salma Saud
Kim, Jin Woong
Cho, Hyung-Ju
Yoon, Joo-Heon
Kim, Chang-Hoon
Development of a Gustatory Function Test for Clinical Application in Korean Subjects
title Development of a Gustatory Function Test for Clinical Application in Korean Subjects
title_full Development of a Gustatory Function Test for Clinical Application in Korean Subjects
title_fullStr Development of a Gustatory Function Test for Clinical Application in Korean Subjects
title_full_unstemmed Development of a Gustatory Function Test for Clinical Application in Korean Subjects
title_short Development of a Gustatory Function Test for Clinical Application in Korean Subjects
title_sort development of a gustatory function test for clinical application in korean subjects
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5823837/
https://www.ncbi.nlm.nih.gov/pubmed/29436203
http://dx.doi.org/10.3349/ymj.2018.59.2.325
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