Calcium phosphate particles stimulate interleukin-1β release from human vascular smooth muscle cells: A role for spleen tyrosine kinase and exosome release

AIMS: Calcium phosphate (CaP) particle deposits are found in several inflammatory diseases including atherosclerosis and osteoarthritis. CaP, and other forms of crystals and particles, can promote inflammasome formation in macrophages leading to caspase-1 activation and secretion of mature interleuk...

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Detalles Bibliográficos
Autores principales: Dautova, Yana, Kapustin, Alexander N., Pappert, Kevin, Epple, Matthias, Okkenhaug, Hanneke, Cook, Simon J., Shanahan, Catherine M., Bootman, Martin D., Proudfoot, Diane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Academic Press 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5823844/
https://www.ncbi.nlm.nih.gov/pubmed/29274344
http://dx.doi.org/10.1016/j.yjmcc.2017.12.007

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