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Reactive Oxygen Species Mediate the Suppression of Arterial Smooth Muscle T-type Ca(2+) Channels by Angiotensin II

Vascular T-type Ca(2+) channels (Ca(V)3.1 and Ca(V)3.2) play a key role in arterial tone development. This study investigated whether this conductance is a regulatory target of angiotensin II (Ang II), a vasoactive peptide that circulates and which is locally produced within the arterial wall. Patch...

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Detalles Bibliográficos
Autores principales: Hashad, Ahmed M., Sancho, Maria, Brett, Suzanne E., Welsh, Donald G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5823855/
https://www.ncbi.nlm.nih.gov/pubmed/29472601
http://dx.doi.org/10.1038/s41598-018-21899-5