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Hakai overexpression effectively induces tumour progression and metastasis in vivo

At early stages of carcinoma progression, epithelial cells undergo a program named epithelial-to-mesenchymal transition characterized by the loss of the major component of the adherens junctions, E-cadherin, which in consequence causes the disruption of cell-cell contacts. Hakai is an E3 ubiquitin-l...

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Detalles Bibliográficos
Autores principales:	Castosa, Raquel, Martinez-Iglesias, Olaia, Roca-Lema, Daniel, Casas-Pais, Alba, Díaz-Díaz, Andrea, Iglesias, Pilar, Santamarina, Isabel, Graña, Begoña, Calvo, Lourdes, Valladares-Ayerbes, Manuel, Concha, Ángel, Figueroa, Angélica
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5823865/ https://www.ncbi.nlm.nih.gov/pubmed/29472634 http://dx.doi.org/10.1038/s41598-018-21808-w

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