Cargando…

HIF-1α hampers dendritic cell function and Th1 generation during chronic visceral leishmaniasis

Inflammation, although responsible for controlling infection, is often associated with the pathogenesis of chronic diseases. Leishmania donovani, the causative agent of visceral leishmaniasis, induces a strong inflammatory response that leads to splenomegaly and ultimately immune suppression. Inflam...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hammami, Akil, Abidin, Belma Melda, Heinonen, Krista M., Stäger, Simona
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5823892/ https://www.ncbi.nlm.nih.gov/pubmed/29472618 http://dx.doi.org/10.1038/s41598-018-21891-z

Ejemplares similares

Infection-adapted emergency hematopoiesis promotes visceral leishmaniasis
por: Abidin, Belma Melda, et al.
Publicado: (2017)

HIF-1α is a key regulator in potentiating suppressor activity and limiting the microbicidal capacity of MDSC-like cells during visceral leishmaniasis
por: Hammami, Akil, et al.
Publicado: (2017)

IRF-5-Mediated Inflammation Limits CD8(+) T Cell Expansion by Inducing HIF-1α and Impairing Dendritic Cell Functions during Leishmania Infection
por: Hammami, Akil, et al.
Publicado: (2015)

Frizzled-6 promotes hematopoietic stem/progenitor cell mobilization and survival during LPS-induced emergency myelopoiesis
por: Nguyen, Trieu Hai, et al.
Publicado: (2022)

The Unknown Nature of the Antigen in the Direct Agglutination Test for Visceral Leishmaniasis Hampers Development of Serodiagnostic Tests
por: Kühne, Vera, et al.
Publicado: (2019)

Targeting HIF-1α Regulatory Pathways as a Strategy to Hamper Tumor-Microenvironment Interactions in CLL
por: Vitale, Candida, et al.
Publicado: (2021)

HIF-1 stabilization in T cells hampers the control of Mycobacterium tuberculosis infection
por: Liu, Ruining, et al.
Publicado: (2022)

Publisher Correction: HIF-1 stabilization in T cells hampers the control of Mycobacterium tuberculosis infection
por: Liu, Ruining, et al.
Publicado: (2022)

Genetic Iron Overload Hampers Development of Cutaneous Leishmaniasis in Mice
por: Charlebois, Edouard, et al.
Publicado: (2023)

Visceral leishmaniasis
por: Sundar, Shyam
Publicado: (2015)

Th1-Biased Immunomodulation and Therapeutic Potential of Artemisia annua in Murine Visceral Leishmaniasis
por: Islamuddin, Mohammad, et al.
Publicado: (2015)

Congenital Visceral Leishmaniasis
por: Boehme, Catharina C., et al.
Publicado: (2006)

Immunity to Visceral Leishmaniasis
por: Ali, Nahid, et al.
Publicado: (2012)

Treatment of Visceral Leishmaniasis
por: Moore, E M, et al.
Publicado: (2010)

Immunobiology of visceral leishmaniasis
por: Kumar, Rajiv, et al.
Publicado: (2012)

Epidemiology of visceral leishmaniasis
por: Ready, Paul D
Publicado: (2014)

Gain-of-function STAT1 mutation and visceral leishmaniasis
por: Lyra, Paula Teixeira, et al.
Publicado: (2022)

VCAM-1 and VLA-4 Modulate Dendritic Cell IL-12p40 Production in Experimental Visceral Leishmaniasis
por: Stanley, Amanda C., et al.
Publicado: (2008)

Galectin-1 Impairs the Generation of Anti-Parasitic Th1 Cell Responses in the Liver during Experimental Visceral Leishmaniasis
por: Bunn, Patrick T., et al.
Publicado: (2017)

TAOK3 limits age-associated inflammation by negatively modulating macrophage differentiation and their production of TNFα
por: Poirier, Alexandre, et al.
Publicado: (2023)

Relationship of Serum Antileishmanial Antibody With Development of Visceral Leishmaniasis, Post-kala-azar Dermal Leishmaniasis and Visceral Leishmaniasis Relapse
por: Mondal, Dinesh, et al.
Publicado: (2019)

Different Expressions of HIF-1α and Metabolism in Brain and Major Visceral Organs of Acute Hypoxic Mice
por: Xu, Lu, et al.
Publicado: (2021)

Visceral Leishmaniasis Treatment, Italy
por: Gradoni, Luigi, et al.
Publicado: (2003)

The reemergence of visceral leishmaniasis in Brazil.
por: Arias, J R, et al.
Publicado: (1996)

Drug Resistance in Visceral Leishmaniasis
por: Maltezou, Helena C.
Publicado: (2010)

Is visceral leishmaniasis a sepsis or not?
por: Puca, E, et al.
Publicado: (2012)

Epidemiology of Visceral Leishmaniasis in Georgia
por: Babuadze, Giorgi, et al.
Publicado: (2014)

Therapeutic Options for Visceral Leishmaniasis
por: Monge-Maillo, Begoña, et al.
Publicado: (2013)

Visceral leishmaniasis with Roth spots
por: Meena, Jagdish, et al.
Publicado: (2014)

Epidemiology of visceral leishmaniasis in Georgia
por: Kokaia, Nora, et al.
Publicado: (2017)

The kinetoplast in the diagnosis of visceral leishmaniasis
por: Murray, Henry W.
Publicado: (2022)

Loss of Hif-2α Rescues the Hif-1α Deletion Phenotype of Neonatal Respiratory Distress In Mice
por: Saini, Yogesh, et al.
Publicado: (2015)

Impaired Phagocytosis in Dendritic Cells From Pediatric Patients With Type 1 Diabetes Does Not Hamper Their Tolerogenic Potential
por: Rodriguez-Fernandez, Silvia, et al.
Publicado: (2019)

VCAM-1 and ICAM-1 Serum Levels as Markers of Relapse in Visceral Leishmaniasis
por: Makis, Alexandros, et al.
Publicado: (2017)

Transcription Factor KLF2 in Dendritic Cells Downregulates Th2 Programming via the HIF-1α/Jagged2/Notch Axis
por: Xiong, Ye, et al.
Publicado: (2016)

Activation of TLR-pathway to induce host Th1 immune response against visceral leishmaniasis: Involvement of galactosylated-flavonoids
por: Pradhan, Supratim, et al.
Publicado: (2022)

Leishmania infantum Induces the Release of sTREM-1 in Visceral Leishmaniasis
por: Bomfim, Lays G. S., et al.
Publicado: (2017)

Evaluation of the diagnostic potential of CD1a immunohistochemistry for visceral leishmaniasis
por: Gadelha, Sami de Andrade Cordeiro, et al.
Publicado: (2019)

Visceral leishmaniasis (kala-azar) and pregnancy.
por: Figueiró-Filho, Ernesto Antonio, et al.
Publicado: (2004)

Asymptomatic Visceral Leishmaniasis, Northern Israel
por: Adini, Irit, et al.
Publicado: (2003)

Cannot write session to /tmp/vufind_sessions/sess_48m7ql59o5sas5mv6ke6u63bqv