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HIF-1α hampers dendritic cell function and Th1 generation during chronic visceral leishmaniasis

Inflammation, although responsible for controlling infection, is often associated with the pathogenesis of chronic diseases. Leishmania donovani, the causative agent of visceral leishmaniasis, induces a strong inflammatory response that leads to splenomegaly and ultimately immune suppression. Inflam...

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Detalles Bibliográficos
Autores principales:	Hammami, Akil, Abidin, Belma Melda, Heinonen, Krista M., Stäger, Simona
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5823892/ https://www.ncbi.nlm.nih.gov/pubmed/29472618 http://dx.doi.org/10.1038/s41598-018-21891-z

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