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Glial cell type-specific changes in spinal dipeptidyl peptidase 4 expression and effects of its inhibitors in inflammatory and neuropatic pain

Altered pain sensations such as hyperalgesia and allodynia are characteristic features of various pain states, and remain difficult to treat. We have shown previously that spinal application of dipeptidyl peptidase 4 (DPP4) inhibitors induces strong antihyperalgesic effect during inflammatory pain....

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Detalles Bibliográficos
Autores principales: Király, Kornél, Kozsurek, Márk, Lukácsi, Erika, Barta, Benjamin, Alpár, Alán, Balázsa, Tamás, Fekete, Csaba, Szabon, Judit, Helyes, Zsuzsanna, Bölcskei, Kata, Tékus, Valéria, Tóth, Zsuzsanna E., Pap, Károly, Gerber, Gábor, Puskár, Zita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5823904/
https://www.ncbi.nlm.nih.gov/pubmed/29472575
http://dx.doi.org/10.1038/s41598-018-21799-8