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GSK3 is a negative regulator of the thermogenic program in brown adipocytes
Brown adipose tissue is a promising therapeutic target in metabolic disorders due to its ability to dissipate energy and improve systemic insulin sensitivity and glucose homeostasis. β-Adrenergic stimulation of brown adipocytes leads to an increase in oxygen consumption and induction of a thermogeni...
Autores principales: | Markussen, Lasse K., Winther, Sally, Wicksteed, Barton, Hansen, Jacob B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5823915/ https://www.ncbi.nlm.nih.gov/pubmed/29472592 http://dx.doi.org/10.1038/s41598-018-21795-y |
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