Sumoylation regulates FMRP-mediated dendritic spine elimination and maturation

Fragile X syndrome (FXS) is the most frequent inherited cause of intellectual disability and the best-studied monogenic cause of autism. FXS results from the functional absence of the fragile X mental retardation protein (FMRP) leading to abnormal pruning and consequently to synaptic communication d...

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Detalles Bibliográficos
Autores principales: Khayachi, Anouar, Gwizdek, Carole, Poupon, Gwénola, Alcor, Damien, Chafai, Magda, Cassé, Frédéric, Maurin, Thomas, Prieto, Marta, Folci, Alessandra, De Graeve, Fabienne, Castagnola, Sara, Gautier, Romain, Schorova, Lenka, Loriol, Céline, Pronot, Marie, Besse, Florence, Brau, Frédéric, Deval, Emmanuel, Bardoni, Barbara, Martin, Stéphane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5823917/
https://www.ncbi.nlm.nih.gov/pubmed/29472612
http://dx.doi.org/10.1038/s41467-018-03222-y

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