scNMT-seq enables joint profiling of chromatin accessibility DNA methylation and transcription in single cells

Parallel single-cell sequencing protocols represent powerful methods for investigating regulatory relationships, including epigenome-transcriptome interactions. Here, we report a single-cell method for parallel chromatin accessibility, DNA methylation and transcriptome profiling. scNMT-seq (single-c...

Descripción completa

Detalles Bibliográficos
Autores principales: Clark, Stephen J., Argelaguet, Ricard, Kapourani, Chantriolnt-Andreas, Stubbs, Thomas M., Lee, Heather J., Alda-Catalinas, Celia, Krueger, Felix, Sanguinetti, Guido, Kelsey, Gavin, Marioni, John C., Stegle, Oliver, Reik, Wolf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5823944/
https://www.ncbi.nlm.nih.gov/pubmed/29472610
http://dx.doi.org/10.1038/s41467-018-03149-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5823944/
https://www.ncbi.nlm.nih.gov/pubmed/29472610
http://dx.doi.org/10.1038/s41467-018-03149-4

Ejemplares similares