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scNMT-seq enables joint profiling of chromatin accessibility DNA methylation and transcription in single cells
Parallel single-cell sequencing protocols represent powerful methods for investigating regulatory relationships, including epigenome-transcriptome interactions. Here, we report a single-cell method for parallel chromatin accessibility, DNA methylation and transcriptome profiling. scNMT-seq (single-c...
Autores principales: | Clark, Stephen J., Argelaguet, Ricard, Kapourani, Chantriolnt-Andreas, Stubbs, Thomas M., Lee, Heather J., Alda-Catalinas, Celia, Krueger, Felix, Sanguinetti, Guido, Kelsey, Gavin, Marioni, John C., Stegle, Oliver, Reik, Wolf |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5823944/ https://www.ncbi.nlm.nih.gov/pubmed/29472610 http://dx.doi.org/10.1038/s41467-018-03149-4 |
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