Cargando…

Model‐Based Reverse Translation Between Veterinary and Human Medicine: The One Health Initiative

There is growing concern about the limitations of rodent models with regard to recapitulation of human disease pathogenesis. Computational modeling of data from humans and animals sharing similar diseases provides an opportunity for parallel drug development in human and veterinary medicine. This “r...

Descripción completa

Detalles Bibliográficos
Autores principales:	Schneider, Benjamin, Balbas‐Martinez, Violeta, Jergens, Albert E., Troconiz, Inaki F., Allenspach, Karin, Mochel, Jonathan P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2017
Materias:	Perspective
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5824107/ https://www.ncbi.nlm.nih.gov/pubmed/29178333 http://dx.doi.org/10.1002/psp4.12262

Ejemplares similares

Intestinal Stem Cells to Advance Drug Development, Precision, and Regenerative Medicine: A Paradigm Shift in Translational Research
por: Mochel, Jonathan P., et al.
Publicado: (2017)

Harnessing the Biology of Canine Intestinal Organoids to Heighten Understanding of Inflammatory Bowel Disease Pathogenesis and Accelerate Drug Discovery: A One Health Approach
por: Kopper, Jamie J., et al.
Publicado: (2021)

Apparent total tract digestibility, fecal characteristics, and blood parameters of healthy adult dogs fed high-fat diets
por: Kilburn, Logan R, et al.
Publicado: (2020)

Confronting Zoonoses, Linking Human and Veterinary Medicine
por: Kahn, Laura H.
Publicado: (2006)

Antimicrobial resistance in livestock and poor quality veterinary medicines
por: Clifford, Katie, et al.
Publicado: (2018)

Self-directed learning in veterinary medicine: are the students ready?
por: Chigerwe, Munashe, et al.
Publicado: (2017)

The Gut-Brain Axis in Neurodegenerative Diseases and Relevance of the Canine Model: A Review
por: Ambrosini, Yoko M., et al.
Publicado: (2019)

Interleukin‐13 and interleukin‐33 mRNA are underexpressed in the duodenal mucosa of German Shepherd dogs with chronic enteropathy
por: Kathrani, Aarti, et al.
Publicado: (2019)

Indoleamine-pyrrole 2,3-dioxygenase-1 (IDO-1) mRNA is over-expressed in the duodenal mucosa and is negatively correlated with serum tryptophan concentrations in dogs with protein-losing enteropathy
por: Kathrani, Aarti, et al.
Publicado: (2019)

Editorial: One Health and Veterinary Regenerative Medicine: Translational Applications
por: Webb, Tracy L., et al.
Publicado: (2022)

Review of Institute of Medicine and National Research Council Recommendations for One Health Initiative
por: Rubin, Carol, et al.
Publicado: (2013)

Biotechnology and Translational Medicine
por: Morrison, BW
Publicado: (2016)

Interleukin-1β expression is increased in the duodenum of dogs with idiopathic inflammatory bowel disease
por: Hawes, Martin, et al.
Publicado: (2018)

Impact of gastrointestinal differences in veterinary species on the oral drug solubility, in vivo dissolution, and formulation of veterinary therapeutics ()
por: Martinez, Marilyn N., et al.
Publicado: (2022)

Proposal for rational antibacterial use in the diagnosis and treatment of dogs with chronic diarrhoea
por: Cerquetella, M., et al.
Publicado: (2020)

Building the European Antimicrobial Resistance Surveillance network in veterinary medicine (EARS-Vet)
por: Mader, Rodolphe, et al.
Publicado: (2021)

Glucocorticoid and dietary effects on mucosal microbiota in canine inflammatory bowel disease
por: Atherly, Todd, et al.
Publicado: (2019)

Derivation of adult canine intestinal organoids for translational research in gastroenterology
por: Chandra, Lawrance, et al.
Publicado: (2019)

International regulatory considerations pertaining to the development of stem cell-based veterinary medicinal products
por: Jeon, Byung-Suk, et al.
Publicado: (2021)

Differential Transcriptomic Profiles Following Stimulation with Lipopolysaccharide in Intestinal Organoids from Dogs with Inflammatory Bowel Disease and Intestinal Mast Cell Tumor
por: Sahoo, Dipak Kumar, et al.
Publicado: (2022)

Focusing on optimality for the translation of precision medicine
por: Kahkoska, Anna R., et al.
Publicado: (2022)

Intranasal Vaccination Strategy to Control the COVID-19 Pandemic from a Veterinary Medicine Perspective
por: Annas, Salleh, et al.
Publicado: (2021)

Retrospective evaluation of toceranib phosphate (Palladia®) use in the treatment of gastrointestinal stromal tumors of dogs
por: Berger, Erika P., et al.
Publicado: (2018)

Convergence of human and veterinary medicine: leveraging canine naturally occurring neurological disorders to develop regenerative treatments
por: Clark, Kaitlin C., et al.
Publicado: (2022)

Pragmatic medicine in solid cancer: a translational alternative to precision medicine
por: Brábek, Jan, et al.
Publicado: (2016)

Roles of contract research organizations in translational medicine
por: Shih, Mei-Shu
Publicado: (2015)

Perspectives on veterinary education in Thailand
por: Nantavisai, Sirirat, et al.
Publicado: (2022)

Leishmaniosis in Greece: The Veterinary Perspective
por: Symeonidou, Isaia, et al.
Publicado: (2023)

OrganoidChip facilitates hydrogel-free immobilization for fast and blur-free imaging of organoids
por: Moshksayan, Khashayar, et al.
Publicado: (2023)

Veterinary informatics: forging the future between veterinary medicine, human medicine, and One Health initiatives—a joint paper by the Association for Veterinary Informatics (AVI) and the CTSA One Health Alliance (COHA)
por: Lustgarten, Jonathan L, et al.
Publicado: (2020)

Using Physiologically Based Pharmacokinetic Modeling for Mechanistic Insight: Cases of Reverse Translation
por: Edginton, Andrea N.
Publicado: (2017)

Cannabis, One Health, and Veterinary Medicine: Cannabinoids’ Role in Public Health, Food Safety, and Translational Medicine
por: Ritter, Sivan, et al.
Publicado: (2020)

Recapitulation of the accessible interface of biopsy-derived canine intestinal organoids to study epithelial-luminal interactions
por: Ambrosini, Yoko M., et al.
Publicado: (2020)

Stem cell translational medicine: The Tianjin model revisited
por: Chen, Haidan
Publicado: (2021)

Pumps, Wires and Pipes: Translating Medicine for our Patients
por: Agusala, Kartik
Publicado: (2021)

COVID-19 and veterinarians for one health, zoonotic- and reverse-zoonotic transmissions
por: Yoo, Han Sang, et al.
Publicado: (2020)

Translational research of one dynamic hip screw system—from the SCI to the FDA
por: Kao, Hung-Chan, et al.
Publicado: (2016)

A systems pharmacology model for inflammatory bowel disease
por: Balbas-Martinez, Violeta, et al.
Publicado: (2018)

A One-Health Model for Reversing Honeybee (Apis mellifera L.) Decline
por: Donkersley, Philip, et al.
Publicado: (2020)

Microbiota-Related Changes in Unconjugated Fecal Bile Acids Are Associated With Naturally Occurring, Insulin-Dependent Diabetes Mellitus in Dogs
por: Jergens, Albert E., et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_q75vo5b72sq77o3pb3o047kr8u