Completion lymphadenectomy for sentinel node positive cutaneous head & neck melanoma

The application and utility of melanoma sentinel lymph node biopsy (SLNB) has evolved significantly since its inception over two decades ago. The current focus has shifted from a staging modality to potentially a therapeutic intervention. Recent research to include large multi‐institutional randomiz...

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Detalles Bibliográficos
Autores principales: Schmalbach, Cecelia E., Bradford, Carol R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Head and Neck, and Tumor Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5824115/
https://www.ncbi.nlm.nih.gov/pubmed/29492467
http://dx.doi.org/10.1002/lio2.136
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author Schmalbach, Cecelia E.
Bradford, Carol R.
author_facet Schmalbach, Cecelia E.
Bradford, Carol R.
author_sort Schmalbach, Cecelia E.
collection PubMed
description The application and utility of melanoma sentinel lymph node biopsy (SLNB) has evolved significantly since its inception over two decades ago. The current focus has shifted from a staging modality to potentially a therapeutic intervention. Recent research to include large multi‐institutional randomized trials have attempted to answer the question: is a completion lymph node dissection (CLND) required following a positive SLNB? This review provides an evidence‐based, contemporary review of the utility of CLND for SLNB positive head and neck cutaneous melanoma patients. LEVEL OF EVIDENCE: NA
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spelling pubmed-58241152018-02-28 Completion lymphadenectomy for sentinel node positive cutaneous head & neck melanoma Schmalbach, Cecelia E. Bradford, Carol R. Laryngoscope Investig Otolaryngol Head and Neck, and Tumor Biology The application and utility of melanoma sentinel lymph node biopsy (SLNB) has evolved significantly since its inception over two decades ago. The current focus has shifted from a staging modality to potentially a therapeutic intervention. Recent research to include large multi‐institutional randomized trials have attempted to answer the question: is a completion lymph node dissection (CLND) required following a positive SLNB? This review provides an evidence‐based, contemporary review of the utility of CLND for SLNB positive head and neck cutaneous melanoma patients. LEVEL OF EVIDENCE: NA John Wiley and Sons Inc. 2018-02-05 /pmc/articles/PMC5824115/ /pubmed/29492467 http://dx.doi.org/10.1002/lio2.136 Text en © 2018 The Authors Laryngoscope Investigative Otolaryngology published by Wiley Periodicals, Inc. on behalf of The Triological Society This is an open access article under the terms of the Creative Commons Attribution‐NonCommercial‐NoDerivs (http://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Head and Neck, and Tumor Biology
Schmalbach, Cecelia E.
Bradford, Carol R.
Completion lymphadenectomy for sentinel node positive cutaneous head & neck melanoma
title Completion lymphadenectomy for sentinel node positive cutaneous head & neck melanoma
title_full Completion lymphadenectomy for sentinel node positive cutaneous head & neck melanoma
title_fullStr Completion lymphadenectomy for sentinel node positive cutaneous head & neck melanoma
title_full_unstemmed Completion lymphadenectomy for sentinel node positive cutaneous head & neck melanoma
title_short Completion lymphadenectomy for sentinel node positive cutaneous head & neck melanoma
title_sort completion lymphadenectomy for sentinel node positive cutaneous head & neck melanoma
topic Head and Neck, and Tumor Biology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5824115/
https://www.ncbi.nlm.nih.gov/pubmed/29492467
http://dx.doi.org/10.1002/lio2.136
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