Pathogenicity and genetic characterisation of a novel reassortant, highly pathogenic avian influenza (HPAI) H5N6 virus isolated in Korea, 2017

We investigated influenza A(H5N6) viruses from migratory birds in Chungnam and Gyeonggi Provinces, South Korea following a reported die-off of poultry in nearby provinces in November 2017. Genetic analysis and virulence studies in chickens and ducks identified our isolate from December 2017 as a nov...

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Detalles Bibliográficos
Autores principales: Kim, Young-Il, Si, Young-Jae, Kwon, Hyeok-Il, Kim, Eun-Ha, Park, Su-Jin, Robles, Norbert John, Nguyen, Hiep Dinh, Yu, Min-Ah, Yu, Kwang-Min, Lee, Youn-Jeong, Lee, Myoung-Heon, Choi, Young Ki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Centre for Disease Prevention and Control (ECDC) 2018
Materias:
Rapid Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5824127/
https://www.ncbi.nlm.nih.gov/pubmed/29463346
http://dx.doi.org/10.2807/1560-7917.ES.2018.23.7.18-00045
Descripción
Sumario:We investigated influenza A(H5N6) viruses from migratory birds in Chungnam and Gyeonggi Provinces, South Korea following a reported die-off of poultry in nearby provinces in November 2017. Genetic analysis and virulence studies in chickens and ducks identified our isolate from December 2017 as a novel highly pathogenic avian influenza virus. It resulted from reassortment between the highly virulent H5N8 strain from Korea with the N6 gene from a low-pathogenic H3N6 virus from the Netherlands.

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