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Pathogenicity and genetic characterisation of a novel reassortant, highly pathogenic avian influenza (HPAI) H5N6 virus isolated in Korea, 2017

We investigated influenza A(H5N6) viruses from migratory birds in Chungnam and Gyeonggi Provinces, South Korea following a reported die-off of poultry in nearby provinces in November 2017. Genetic analysis and virulence studies in chickens and ducks identified our isolate from December 2017 as a nov...

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Autores principales: Kim, Young-Il, Si, Young-Jae, Kwon, Hyeok-Il, Kim, Eun-Ha, Park, Su-Jin, Robles, Norbert John, Nguyen, Hiep Dinh, Yu, Min-Ah, Yu, Kwang-Min, Lee, Youn-Jeong, Lee, Myoung-Heon, Choi, Young Ki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Centre for Disease Prevention and Control (ECDC) 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5824127/
https://www.ncbi.nlm.nih.gov/pubmed/29463346
http://dx.doi.org/10.2807/1560-7917.ES.2018.23.7.18-00045
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author Kim, Young-Il
Si, Young-Jae
Kwon, Hyeok-Il
Kim, Eun-Ha
Park, Su-Jin
Robles, Norbert John
Nguyen, Hiep Dinh
Yu, Min-Ah
Yu, Kwang-Min
Lee, Youn-Jeong
Lee, Myoung-Heon
Choi, Young Ki
author_facet Kim, Young-Il
Si, Young-Jae
Kwon, Hyeok-Il
Kim, Eun-Ha
Park, Su-Jin
Robles, Norbert John
Nguyen, Hiep Dinh
Yu, Min-Ah
Yu, Kwang-Min
Lee, Youn-Jeong
Lee, Myoung-Heon
Choi, Young Ki
author_sort Kim, Young-Il
collection PubMed
description We investigated influenza A(H5N6) viruses from migratory birds in Chungnam and Gyeonggi Provinces, South Korea following a reported die-off of poultry in nearby provinces in November 2017. Genetic analysis and virulence studies in chickens and ducks identified our isolate from December 2017 as a novel highly pathogenic avian influenza virus. It resulted from reassortment between the highly virulent H5N8 strain from Korea with the N6 gene from a low-pathogenic H3N6 virus from the Netherlands.
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spelling pubmed-58241272018-09-04 Pathogenicity and genetic characterisation of a novel reassortant, highly pathogenic avian influenza (HPAI) H5N6 virus isolated in Korea, 2017 Kim, Young-Il Si, Young-Jae Kwon, Hyeok-Il Kim, Eun-Ha Park, Su-Jin Robles, Norbert John Nguyen, Hiep Dinh Yu, Min-Ah Yu, Kwang-Min Lee, Youn-Jeong Lee, Myoung-Heon Choi, Young Ki Euro Surveill Rapid Communication We investigated influenza A(H5N6) viruses from migratory birds in Chungnam and Gyeonggi Provinces, South Korea following a reported die-off of poultry in nearby provinces in November 2017. Genetic analysis and virulence studies in chickens and ducks identified our isolate from December 2017 as a novel highly pathogenic avian influenza virus. It resulted from reassortment between the highly virulent H5N8 strain from Korea with the N6 gene from a low-pathogenic H3N6 virus from the Netherlands. European Centre for Disease Prevention and Control (ECDC) 2018-02-15 /pmc/articles/PMC5824127/ /pubmed/29463346 http://dx.doi.org/10.2807/1560-7917.ES.2018.23.7.18-00045 Text en This article is copyright of The Authors, 2018. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution (CC BY 4.0) Licence. You may share and adapt the material, but must give appropriate credit to the source, provide a link to the licence, and indicate if changes were made.
spellingShingle Rapid Communication
Kim, Young-Il
Si, Young-Jae
Kwon, Hyeok-Il
Kim, Eun-Ha
Park, Su-Jin
Robles, Norbert John
Nguyen, Hiep Dinh
Yu, Min-Ah
Yu, Kwang-Min
Lee, Youn-Jeong
Lee, Myoung-Heon
Choi, Young Ki
Pathogenicity and genetic characterisation of a novel reassortant, highly pathogenic avian influenza (HPAI) H5N6 virus isolated in Korea, 2017
title Pathogenicity and genetic characterisation of a novel reassortant, highly pathogenic avian influenza (HPAI) H5N6 virus isolated in Korea, 2017
title_full Pathogenicity and genetic characterisation of a novel reassortant, highly pathogenic avian influenza (HPAI) H5N6 virus isolated in Korea, 2017
title_fullStr Pathogenicity and genetic characterisation of a novel reassortant, highly pathogenic avian influenza (HPAI) H5N6 virus isolated in Korea, 2017
title_full_unstemmed Pathogenicity and genetic characterisation of a novel reassortant, highly pathogenic avian influenza (HPAI) H5N6 virus isolated in Korea, 2017
title_short Pathogenicity and genetic characterisation of a novel reassortant, highly pathogenic avian influenza (HPAI) H5N6 virus isolated in Korea, 2017
title_sort pathogenicity and genetic characterisation of a novel reassortant, highly pathogenic avian influenza (hpai) h5n6 virus isolated in korea, 2017
topic Rapid Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5824127/
https://www.ncbi.nlm.nih.gov/pubmed/29463346
http://dx.doi.org/10.2807/1560-7917.ES.2018.23.7.18-00045
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