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Hypothalamic POMC expression is required for peripheral insulin action on hepatic gluconeogenesis through regulating STAT3 in sepsis rats

Liver injury and dysregulated glucose homoeostasis are common manifestations during sepsis. Although plenty of studies reported insulin could protect against multiple organ injuries caused by critical infections among patients, little was known about the precise mechanism. We investigated whether li...

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Detalles Bibliográficos
Autores principales: Feng, Bin, Zhang, Nannan, Duan, Kaipeng, Shi, Bimin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5824389/
https://www.ncbi.nlm.nih.gov/pubmed/29285858
http://dx.doi.org/10.1111/jcmm.13449