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Testosterone regulates the expression and functional activity of sphingosine‐1‐phosphate receptors in the rat corpus cavernosum

The bioactive lipid sphingosine‐1‐phosphate (S1P) regulates smooth muscle (SM) contractility predominantly via three G protein‐coupled receptors. The S1P1 receptor is associated with nitric oxide (NO)‐mediated SM relaxation, while S1P2 & S1P3 receptors are linked to SM contraction via activation...

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Detalles Bibliográficos
Autores principales: Yin, Jing, Guo, Yu‐ming, Chen, Ping, Xiao, He, Wang, Xing‐huan, DiSanto, Michael E, Zhang, Xin‐hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5824404/
https://www.ncbi.nlm.nih.gov/pubmed/29266713
http://dx.doi.org/10.1111/jcmm.13416

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