Cargando…

Hyper‐acetylation contributes to the sensitivity of chemo‐resistant prostate cancer cells to histone deacetylase inhibitor Trichostatin A

Therapeutic agents are urgently needed for treating metastatic castration‐refractory prostate cancer (mCRPC) that is unresponsive to androgen deprivation and chemotherapy. Our screening assays demonstrated that chemotherapy‐resistant prostate cancer (PCa) cells are more sensitive to HDAC inhibitors...

Descripción completa

Detalles Bibliográficos
Autores principales:	Xu, Qingqing, Liu, Xiaofei, Zhu, Shiqin, Hu, Xuelei, Niu, Huanmin, Zhang, Xiulei, Zhu, Deyu, Nesa, Effat Un, Tian, Keli, Yuan, Huiqing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2018
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5824406/ https://www.ncbi.nlm.nih.gov/pubmed/29327812 http://dx.doi.org/10.1111/jcmm.13475

Ejemplares similares

The histone deacetylase inhibitor Trichostatin A modulates CD4+ T cell responses
por: Moreira, José Manuel Afonso, et al.
Publicado: (2003)

Sequence-Dependent Radiosensitization of Histone Deacetylase Inhibitors Trichostatin A and SK-7041
por: Kim, Jin Ho, et al.
Publicado: (2013)

Histone Deacetylase Inhibitor Trichostatin A Ameliorated Endotoxin-Induced Neuroinflammation and Cognitive Dysfunction
por: Hsing, Chung-Hsi, et al.
Publicado: (2015)

Downregulation of reticulocalbin‐1 differentially facilitates apoptosis and necroptosis in human prostate cancer cells
por: Liu, Xiaofei, et al.
Publicado: (2018)

Acetylation and Histone Deacetylase Inhibitors in Cancer
por: Kortenhorst, Madeleine S. Q., et al.
Publicado: (2006)

The histone deacetylase inhibitor trichostatin A alters the pattern of DNA replication origin activity in human cells
por: Kemp, Michael G., et al.
Publicado: (2005)

The histone deacetylase inhibitor trichostatin A alters the pattern of DNA replication origin activity in human cells
por: Kemp, Michael G., et al.
Publicado: (2005)

Transcriptional regulation of human osteopontin promoter by histone deacetylase inhibitor, trichostatin A in cervical cancer cells
por: Sharma, Priyanka, et al.
Publicado: (2010)

Effects of histone deacetylase inhibitor trichostatin A combined with cisplatin on apoptosis of A549 cell line
por: Zhang, Xuan, et al.
Publicado: (2015)

Histone deacetylase inhibitor trichostatin A sensitises cisplatin-resistant ovarian cancer cells to oncolytic adenovirus
por: Hulin-Curtis, Sarah L., et al.
Publicado: (2018)

Impact of a Histone Deacetylase Inhibitor—Trichostatin A on Neurogenesis after Hypoxia-Ischemia in Immature Rats
por: Zalewska, Teresa, et al.
Publicado: (2020)

Improved Therapeutic Effect against Leukemia by a Combination of the Histone Methyltransferase Inhibitor Chaetocin and the Histone Deacetylase Inhibitor Trichostatin A
por: Tran, Huong Thi Thanh, et al.
Publicado: (2013)

Histone acetylation and the role of histone deacetylases in normal cyclic endometrium
por: Gujral, Palak, et al.
Publicado: (2020)

Myelodysplastic Syndrome and Histone Deacetylase Inhibitors: “To Be or Not to Be Acetylated”?
por: Stintzing, Sebastian, et al.
Publicado: (2011)

Trichostatin A, a histone deacetylase inhibitor suppresses NADPH Oxidase 4‐Derived Redox Signalling and Angiogenesis
por: Hakami, Nora Y., et al.
Publicado: (2016)

Trichostatin A, a Histone Deacetylase Inhibitor, Alleviates Eosinophilic Meningitis Induced by Angiostrongylus cantonensis Infection in Mice
por: Zhang, Yanhua, et al.
Publicado: (2019)

Histone deacetylase 3 indirectly modulates tubulin acetylation
por: Bacon, Travis, et al.
Publicado: (2015)

Neuroprotection by the histone deacetylase inhibitor trichostatin A in a model of lipopolysaccharide-sensitised neonatal hypoxic-ischaemic brain injury
por: Fleiss, Bobbi, et al.
Publicado: (2012)

Trichostatin A, a histone deacetylase inhibitor, suppresses proliferation and epithelial–mesenchymal transition in retinal pigment epithelium cells
por: Xiao, Wei, et al.
Publicado: (2014)

Effect of histone deacetylase inhibitors trichostatin A and valproic acid on hair cell regeneration in zebrafish lateral line neuromasts
por: He, Yingzi, et al.
Publicado: (2014)

Histone Deacetylase Inhibitor Trichostatin a Promotes the Apoptosis of Osteosarcoma Cells through p53 Signaling Pathway Activation
por: Deng, Zhantao, et al.
Publicado: (2016)

Anterior gradient 2 increases long-chain fatty acid uptake via stabilizing FABP1 and facilitates lipid accumulation
por: Wang, Yunqiu, et al.
Publicado: (2021)

Synergistic activity of the histone deacetylase inhibitor trichostatin A and the proteasome inhibitor PS-341 against taxane-resistant ovarian cancer cell lines
por: Jin, Xin, et al.
Publicado: (2017)

Trichostatin A induces 5-lipoxygenase promoter activity and mRNA expression via inhibition of histone deacetylase 2 and 3
por: Pufahl, Laura, et al.
Publicado: (2012)

The epigenetic modifier trichostatin A, a histone deacetylase inhibitor, suppresses proliferation and epithelial–mesenchymal transition of lens epithelial cells
por: Chen, X, et al.
Publicado: (2013)

Histone Deacetylase Inhibitors Trichostatin A and MCP30 Relieve Benzene-Induced Hematotoxicity via Restoring Topoisomerase IIα
por: Chen, Jingjing, et al.
Publicado: (2016)

Histone Deacetylase Inhibitor, Trichostatin A, Synergistically Enhances Paclitaxel-Induced Cytotoxicity in Urothelial Carcinoma Cells by Suppressing the ERK Pathway
por: Hsu, Fu-Shun, et al.
Publicado: (2019)

Histone Deacetylase Inhibitor Trichostatin A Reduces Endothelial Cell Proliferation by Suppressing STAT5A-Related Gene Transcription
por: Li, Yize, et al.
Publicado: (2021)

Histone deacetylases control lysine acetylation of ribosomal proteins in rice
por: Xu, Qiutao, et al.
Publicado: (2021)

Histone deacetylase inhibitor, Trichostatin A induces ubiquitin-dependent cyclin D1 degradation in MCF-7 breast cancer cells
por: Alao, John P, et al.
Publicado: (2006)

The histone deacetylase inhibitor trichostatin a decreases lymphangiogenesis by inducing apoptosis and cell cycle arrest via p21-dependent pathways
por: Hrgovic, Igor, et al.
Publicado: (2016)

PI3K/mTOR dual inhibitor BEZ235 and histone deacetylase inhibitor Trichostatin A synergistically exert anti-tumor activity in breast cancer
por: Chen, Liyan, et al.
Publicado: (2017)

Evaluation of histone deacetylase inhibitor substituted zinc and indium phthalocyanines for chemo- and photodynamic therapy
por: Aru, Başak, et al.
Publicado: (2021)

Dysferlin Interacts with Histone Deacetylase 6 and Increases alpha-Tubulin Acetylation
por: Di Fulvio, Sabrina, et al.
Publicado: (2011)

Histone Acetylation Level and Histone Acetyltransferase/Deacetylase Activity in Ejaculated Sperm from Normozoospermic Men
por: Kim, Jee Hyun, et al.
Publicado: (2014)

Histone deacetylase (HDAC) 1 and 2 complexes regulate both histone acetylation and crotonylation in vivo
por: Kelly, R. D. W., et al.
Publicado: (2018)

Methylation-directed acetylation of histone H3 regulates developmental sensitivity to histone deacetylase inhibition
por: Huang, Li-Yao, et al.
Publicado: (2021)

The anti-tumor effects of dual PI3K/mTOR inhibitor BEZ235 and histone deacetylase inhibitor Trichostatin A on inducing autophagy in esophageal squamous cell carcinoma
por: Wu, Ning, et al.
Publicado: (2018)

Inactivation of TFEB and NF-κB by marchantin M alleviates the chemotherapy-driven pro-tumorigenic senescent secretion
por: Niu, Huanmin, et al.
Publicado: (2019)

Histone Deacetylases and Histone Deacetylase Inhibitors in Neuroblastoma
por: Phimmachanh, Monica, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_6eb8kh19b75k4l2hitm8uv70ap