Cargando…

IGF-1 as a Drug for Preterm Infants: A Step-Wise Clinical Development

BACKGROUND: Insulin-like growth factor 1 (IGF-1) is a mitogenic hormone involved in many processes such as growth, metabolism, angiogenesis and differentiation. After very preterm birth, energy demands increase while maternal supplies of nutrients and other factors are lost and the infant may become...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hellström, Ann, Ley, David, Hallberg, Boubou, Löfqvist, Chatarina, Hansen-Pupp, Ingrid, Ramenghi, Luca A., Borg, Jan, Smith, Lois E. H., Hård, Anna-Lena
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Bentham Science Publishers 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5824464/ https://www.ncbi.nlm.nih.gov/pubmed/28969546 http://dx.doi.org/10.2174/1381612823666171002114545

Ejemplares similares

Insulin‐like growth factor 1 has multisystem effects on foetal and preterm infant development
por: Hellström, Ann, et al.
Publicado: (2016)

IGF1, serum glucose, and retinopathy of prematurity in extremely preterm infants
por: Cakir, Bertan, et al.
Publicado: (2020)

Unpasteurised maternal breast milk is positively associated with growth outcomes in extremely preterm infants
por: Lund, Anna‐My, et al.
Publicado: (2019)

Increased postnatal concentrations of pro-inflammatory cytokines are associated with reduced IGF-I levels and retinopathy of prematurity
por: Hellgren, Gunnel, et al.
Publicado: (2017)

Analysis of Brain Injury Biomarker Neurofilament Light and Neurodevelopmental Outcomes and Retinopathy of Prematurity Among Preterm Infants
por: Sjöbom, Ulrika, et al.
Publicado: (2021)

Randomized Control Trial of Postnatal rhIGF-1/rhIGFBP-3 Replacement in Preterm Infants: Post-hoc Analysis of Its Effect on Brain Injury
por: Horsch, Sandra, et al.
Publicado: (2020)

Serum choline in extremely preterm infants declines with increasing parenteral nutrition
por: Nilsson, Anders K., et al.
Publicado: (2020)

Low postnatal serum IGF-I levels are associated with bronchopulmonary dysplasia (BPD)
por: Löfqvist, Chatarina, et al.
Publicado: (2012)

rhIGF-1/rhIGFBP-3 in Preterm Infants: A Phase 2 Randomized Controlled Trial
por: Ley, David, et al.
Publicado: (2018)

Postnatal serum IGF-1 levels associate with brain volumes at term in extremely preterm infants
por: Hellström, William, et al.
Publicado: (2022)

Modification of serum fatty acids in preterm infants by parenteral lipids and enteral docosahexaenoic acid/arachidonic acid: A secondary analysis of the Mega Donna Mega trial
por: Sjöbom, Ulrika, et al.
Publicado: (2023)

WINROP Identifies Severe Retinopathy of Prematurity at an Early Stage in a Nation-Based Cohort of Extremely Preterm Infants
por: Lundgren, Pia, et al.
Publicado: (2013)

Review shows that donor milk does not promote the growth and development of preterm infants as well as maternal milk
por: Hård, Anna‐Lena, et al.
Publicado: (2019)

Effect of Enteral Lipid Supplement on Severe Retinopathy of Prematurity: A Randomized Clinical Trial
por: Hellström, Ann, et al.
Publicado: (2021)

Association of Docosahexaenoic Acid and Arachidonic Acid Serum Levels With Retinopathy of Prematurity in Preterm Infants
por: Hellström, Ann, et al.
Publicado: (2021)

Neonatal IGF-1/IGFBP-1 axis and retinopathy of prematurity are associated with increased blood pressure in preterm children
por: Kistner, Anna, et al.
Publicado: (2014)

Decreased Platelet Counts and Serum Levels of VEGF-A, PDGF-BB, and BDNF in Extremely Preterm Infants Developing Severe ROP
por: Hellgren, Gunnel, et al.
Publicado: (2021)

Longitudinal Serum Metabolomics in Extremely Premature Infants: Relationships With Gestational Age, Nutrition, and Morbidities
por: Nilsson, Anders K., et al.
Publicado: (2022)

Visual outcome at 2.5 years of age in ω-3 and ω-6 long-chain polyunsaturated fatty acid supplemented preterm infants: a follow-up of a randomized controlled trial
por: Lundgren, Pia, et al.
Publicado: (2023)

Early single-channel aEEG/EEG predicts outcome in very preterm infants
por: Wikström, Sverre, et al.
Publicado: (2012)

Low Birth Weight Is a Risk Factor for Severe Retinopathy of Prematurity Depending on Gestational Age
por: Lundgren, Pia, et al.
Publicado: (2014)

Implementing higher oxygen saturation targets reduced the impact of poor weight gain as a predictor for retinopathy of prematurity
por: Lundgren, Pia, et al.
Publicado: (2017)

Influence of Human Milk and Parenteral Lipid Emulsions on Serum Fatty Acid Profiles in Extremely Preterm Infants
por: Nilsson, Anders K., et al.
Publicado: (2018)

Systematic review of the healthcare cost of bronchopulmonary dysplasia
por: Humayun, Jhangir, et al.
Publicado: (2021)

The development of blood protein profiles in extremely preterm infants follows a stereotypic evolution pattern
por: Zhong, Wen, et al.
Publicado: (2023)

Mother's Own Milk and Its Relationship to Growth and Morbidity in a Population-based Cohort of Extremely Preterm Infants
por: Lund, Anna-My, et al.
Publicado: (2022)

Long‐chain polyunsaturated fatty acids decline rapidly in milk from mothers delivering extremely preterm indicating the need for supplementation
por: Nilsson, Anders K., et al.
Publicado: (2018)

Preterm infant circulating sex steroid levels are not altered by transfusion with adult male plasma: a retrospective multicentre cohort study
por: Nilsson, Anders K, et al.
Publicado: (2022)

Effects of a lipid emulsion containing fish oil on polyunsaturated fatty acid profiles, growth and morbidities in extremely premature infants: A randomized controlled trial
por: Najm, Svetlana, et al.
Publicado: (2017)

Cohort study of growth patterns by gestational age in preterm infants developing morbidity
por: Klevebro, S, et al.
Publicado: (2016)

Association of Retinopathy of Prematurity With Low Levels of Arachidonic Acid: A Secondary Analysis of a Randomized Clinical Trial
por: Löfqvist, Chatarina A., et al.
Publicado: (2018)

Evaluation of the Retinopathy of Prematurity Activity Scale (ROP-ActS) in a randomised controlled trial aiming for prevention of severe ROP: a substudy of the Mega Donna Mega trial
por: Pivodic, Aldina, et al.
Publicado: (2022)

Costs associated with retinopathy of prematurity: a systematic review and meta-analysis
por: Gyllensten, Hanna, et al.
Publicado: (2022)

A systematic review and meta-analysis of preanalytical factors and methodological differences influencing the measurement of circulating vascular endothelial growth factor
por: Sjöbom, Ulrika, et al.
Publicado: (2022)

Low fraction of fetal haemoglobin is associated with retinopathy of prematurity in the very preterm infant
por: Hellström, William, et al.
Publicado: (2022)

Neonatal hyperglycaemia is associated with worse neurodevelopmental outcomes in extremely preterm infants
por: Zamir, Itay, et al.
Publicado: (2021)

Prevalence of Severe Visual Disability Among Preterm Children With Retinopathy of Prematurity and Association With Adherence to Best Practice Guidelines
por: Norman, Mikael, et al.
Publicado: (2019)

Photoreceptor glucose metabolism determines normal retinal vascular growth
por: Fu, Zhongjie, et al.
Publicado: (2017)

Hyper high haemoglobin content in red blood cells and erythropoietic transitions postnatally in infants of 22 to 26 weeks’ gestation: a prospective cohort study
por: Larsson, Sara Marie, et al.
Publicado: (2023)

Individual Risk Prediction for Sight-Threatening Retinopathy of Prematurity Using Birth Characteristics
por: Pivodic, Aldina, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_t8n3m3rdavrqlvnmbumedr3k7n