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Solid lipid curcumin particles provide greater anti-amyloid, anti-inflammatory and neuroprotective effects than curcumin in the 5xFAD mouse model of Alzheimer’s disease

BACKGROUND: Neuroinflammation and the presence of amyloid beta protein (Aβ) and neurofibrillary tangles are key pathologies in Alzheimer’s disease (AD). As a potent anti-amyloid and anti-inflammatory natural polyphenol, curcumin (Cur) could be potential therapies for AD. Unfortunately, poor solubili...

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Detalles Bibliográficos
Autores principales:	Maiti, Panchanan, Paladugu, Leela, Dunbar, Gary L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5824468/ https://www.ncbi.nlm.nih.gov/pubmed/29471781 http://dx.doi.org/10.1186/s12868-018-0406-3

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