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Unique CD44 intronic SNP is associated with tumor grade in breast cancer: a case control study and in silico analysis
BACKGROUND: CD44 encoded by a single gene is a cell surface transmembrane glycoprotein. Exon 2 is one of the important exons to bind CD44 protein to hyaluronan. Experimental evidences show that hyaluronan–CD44 interaction intensifies the proliferation, migration, and invasion of breast cancer cells....
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5824488/ https://www.ncbi.nlm.nih.gov/pubmed/29483847 http://dx.doi.org/10.1186/s12935-018-0522-2 |