A curious case of central odontogenic fibroma: A novel perspective

We appraise a case of central odontogenic fibroma (COF) with unusual histologic features of entrapped neural elements and mast cells. The presence of mast cells attributed to the release of stem cell factor, the principal growth and activating factor of mast cells. A putative role for C-kit and mast...

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Detalles Bibliográficos
Autores principales: Chandrashekar, Chetana, Sen, Subhalakshmi, Narayanaswamy, Venkadasalapathi, Radhakrishnan, Raghu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2018
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5824509/
https://www.ncbi.nlm.nih.gov/pubmed/29491598
http://dx.doi.org/10.4103/jomfp.JOMFP_156_16
Descripción
Sumario:We appraise a case of central odontogenic fibroma (COF) with unusual histologic features of entrapped neural elements and mast cells. The presence of mast cells attributed to the release of stem cell factor, the principal growth and activating factor of mast cells. A putative role for C-kit and mast cells in the pathogenesis of COF is described.

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