A curious case of central odontogenic fibroma: A novel perspective

We appraise a case of central odontogenic fibroma (COF) with unusual histologic features of entrapped neural elements and mast cells. The presence of mast cells attributed to the release of stem cell factor, the principal growth and activating factor of mast cells. A putative role for C-kit and mast...

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Autores principales: Chandrashekar, Chetana, Sen, Subhalakshmi, Narayanaswamy, Venkadasalapathi, Radhakrishnan, Raghu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2018
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5824509/
https://www.ncbi.nlm.nih.gov/pubmed/29491598
http://dx.doi.org/10.4103/jomfp.JOMFP_156_16
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author Chandrashekar, Chetana
Sen, Subhalakshmi
Narayanaswamy, Venkadasalapathi
Radhakrishnan, Raghu
author_facet Chandrashekar, Chetana
Sen, Subhalakshmi
Narayanaswamy, Venkadasalapathi
Radhakrishnan, Raghu
author_sort Chandrashekar, Chetana
collection PubMed
description We appraise a case of central odontogenic fibroma (COF) with unusual histologic features of entrapped neural elements and mast cells. The presence of mast cells attributed to the release of stem cell factor, the principal growth and activating factor of mast cells. A putative role for C-kit and mast cells in the pathogenesis of COF is described.
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spelling pubmed-58245092018-02-28 A curious case of central odontogenic fibroma: A novel perspective Chandrashekar, Chetana Sen, Subhalakshmi Narayanaswamy, Venkadasalapathi Radhakrishnan, Raghu J Oral Maxillofac Pathol Case Report We appraise a case of central odontogenic fibroma (COF) with unusual histologic features of entrapped neural elements and mast cells. The presence of mast cells attributed to the release of stem cell factor, the principal growth and activating factor of mast cells. A putative role for C-kit and mast cells in the pathogenesis of COF is described. Medknow Publications & Media Pvt Ltd 2018-01 /pmc/articles/PMC5824509/ /pubmed/29491598 http://dx.doi.org/10.4103/jomfp.JOMFP_156_16 Text en Copyright: © 2018 Journal of Oral and Maxillofacial Pathology http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms.
spellingShingle Case Report
Chandrashekar, Chetana
Sen, Subhalakshmi
Narayanaswamy, Venkadasalapathi
Radhakrishnan, Raghu
A curious case of central odontogenic fibroma: A novel perspective
title A curious case of central odontogenic fibroma: A novel perspective
title_full A curious case of central odontogenic fibroma: A novel perspective
title_fullStr A curious case of central odontogenic fibroma: A novel perspective
title_full_unstemmed A curious case of central odontogenic fibroma: A novel perspective
title_short A curious case of central odontogenic fibroma: A novel perspective
title_sort curious case of central odontogenic fibroma: a novel perspective
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5824509/
https://www.ncbi.nlm.nih.gov/pubmed/29491598
http://dx.doi.org/10.4103/jomfp.JOMFP_156_16
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