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Insulin/IGF-driven cancer cell-stroma crosstalk as a novel therapeutic target in pancreatic cancer

Pancreatic ductal adenocarcinoma (PDAC) is unrivalled the deadliest gastrointestinal cancer in the western world. There is substantial evidence implying that insulin and insulin-like growth factor (IGF) signaling axis prompt PDAC into an advanced stage by enhancing tumor growth, metastasis and by dr...

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Detalles Bibliográficos
Autores principales:	Mutgan, Ayse Ceren, Besikcioglu, H. Erdinc, Wang, Shenghan, Friess, Helmut, Ceyhan, Güralp O., Demir, Ihsan Ekin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5824531/ https://www.ncbi.nlm.nih.gov/pubmed/29475434 http://dx.doi.org/10.1186/s12943-018-0806-0

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