Cargando…

A maximum likelihood algorithm for reconstructing 3D structures of human chromosomes from chromosomal contact data

BACKGROUND: The development of chromosomal conformation capture techniques, particularly, the Hi-C technique, has made the analysis and study of the spatial conformation of a genome an important topic in bioinformatics and computational biology. Aided by high-throughput next generation sequencing te...

Descripción completa

Detalles Bibliográficos
Autores principales: Oluwadare, Oluwatosin, Zhang, Yuxiang, Cheng, Jianlin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5824572/
https://www.ncbi.nlm.nih.gov/pubmed/29471801
http://dx.doi.org/10.1186/s12864-018-4546-8