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A maximum likelihood algorithm for reconstructing 3D structures of human chromosomes from chromosomal contact data
BACKGROUND: The development of chromosomal conformation capture techniques, particularly, the Hi-C technique, has made the analysis and study of the spatial conformation of a genome an important topic in bioinformatics and computational biology. Aided by high-throughput next generation sequencing te...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5824572/ https://www.ncbi.nlm.nih.gov/pubmed/29471801 http://dx.doi.org/10.1186/s12864-018-4546-8 |