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Endophenotypes in psychiatric disease: prospects and challenges
Endophenotypes, quantitative neurobehavioral traits that index genetic susceptibility for a psychiatric disorder, have been examined in thousands of studies. Nevertheless, they have underexploited potential to provide etiological insights into prognosis, how psychopathology develops, the etiology of...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5824588/ https://www.ncbi.nlm.nih.gov/pubmed/29471866 http://dx.doi.org/10.1186/s13073-018-0526-5 |
| _version_ | 1783302058013622272 |
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| author | Iacono, William G. |
| author_facet | Iacono, William G. |
| author_sort | Iacono, William G. |
| collection | PubMed |
| description | Endophenotypes, quantitative neurobehavioral traits that index genetic susceptibility for a psychiatric disorder, have been examined in thousands of studies. Nevertheless, they have underexploited potential to provide etiological insights into prognosis, how psychopathology develops, the etiology of comorbidity, and the mechanisms of gene function. |
| format | Online Article Text |
| id | pubmed-5824588 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2018 |
| publisher | BioMed Central |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-58245882018-02-26 Endophenotypes in psychiatric disease: prospects and challenges Iacono, William G. Genome Med Comment Endophenotypes, quantitative neurobehavioral traits that index genetic susceptibility for a psychiatric disorder, have been examined in thousands of studies. Nevertheless, they have underexploited potential to provide etiological insights into prognosis, how psychopathology develops, the etiology of comorbidity, and the mechanisms of gene function. BioMed Central 2018-02-22 /pmc/articles/PMC5824588/ /pubmed/29471866 http://dx.doi.org/10.1186/s13073-018-0526-5 Text en © The Author(s). 2018 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. |
| spellingShingle | Comment Iacono, William G. Endophenotypes in psychiatric disease: prospects and challenges |
| title | Endophenotypes in psychiatric disease: prospects and challenges |
| title_full | Endophenotypes in psychiatric disease: prospects and challenges |
| title_fullStr | Endophenotypes in psychiatric disease: prospects and challenges |
| title_full_unstemmed | Endophenotypes in psychiatric disease: prospects and challenges |
| title_short | Endophenotypes in psychiatric disease: prospects and challenges |
| title_sort | endophenotypes in psychiatric disease: prospects and challenges |
| topic | Comment |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5824588/ https://www.ncbi.nlm.nih.gov/pubmed/29471866 http://dx.doi.org/10.1186/s13073-018-0526-5 |
| work_keys_str_mv | AT iaconowilliamg endophenotypesinpsychiatricdiseaseprospectsandchallenges |