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Evaluation of agonist and antagonist radioligands for somatostatin receptor imaging of breast cancer using positron emission tomography

BACKGROUND: The somatostatin receptor subtype 2 (sstr2) is expressed on a majority of luminal breast cancers, however SPECT and scintigraphy imaging with agonistic sstr2 probes has been sub-optimal. High affinity antagonists can access more binding sites on the cell surface, resulting in higher tumo...

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Detalles Bibliográficos
Autores principales: Dude, Iulia, Zhang, Zhengxing, Rousseau, Julie, Hundal-Jabal, Navjit, Colpo, Nadine, Merkens, Helen, Lin, Kuo-Shyan, Bénard, François
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5824694/
https://www.ncbi.nlm.nih.gov/pubmed/29503845
http://dx.doi.org/10.1186/s41181-017-0023-y