Cargando…

Evaluation of agonist and antagonist radioligands for somatostatin receptor imaging of breast cancer using positron emission tomography

BACKGROUND: The somatostatin receptor subtype 2 (sstr2) is expressed on a majority of luminal breast cancers, however SPECT and scintigraphy imaging with agonistic sstr2 probes has been sub-optimal. High affinity antagonists can access more binding sites on the cell surface, resulting in higher tumo...

Descripción completa

Detalles Bibliográficos
Autores principales:	Dude, Iulia, Zhang, Zhengxing, Rousseau, Julie, Hundal-Jabal, Navjit, Colpo, Nadine, Merkens, Helen, Lin, Kuo-Shyan, Bénard, François
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer International Publishing 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5824694/ https://www.ncbi.nlm.nih.gov/pubmed/29503845 http://dx.doi.org/10.1186/s41181-017-0023-y

Ejemplares similares

(18)F-Labeled Cyclized α-Melanocyte-Stimulating Hormone Derivatives for Imaging Human Melanoma Xenograft with Positron Emission Tomography
por: Zhang, Chengcheng, et al.
Publicado: (2019)

Preclinical Melanoma Imaging with (68)Ga-Labeled α-Melanocyte-Stimulating Hormone Derivatives Using PET
por: Zhang, Chengcheng, et al.
Publicado: (2017)

Monosodium Glutamate Reduces (68)Ga-PSMA-11 Uptake in Salivary Glands and Kidneys in a Preclinical Prostate Cancer Model
por: Rousseau, Etienne, et al.
Publicado: (2018)

Selective Cyclized α-Melanocyte-Stimulating Hormone Derivative with Multiple N-Methylations for Melanoma Imaging with Positron Emission Tomography
por: Zhang, Chengcheng, et al.
Publicado: (2020)

What a difference a methylene makes: replacing Glu with Asp or Aad in the Lys-urea-Glu pharmacophore of PSMA-targeting radioligands to reduce kidney and salivary gland uptake
por: Kuo, Hsiou-Ting, et al.
Publicado: (2022)

Synthesis and Evaluation of (99m)Tc-Labeled PSMA-Targeted Tracers Based on the Lys-Urea-Aad Pharmacophore for Detecting Prostate Cancer with Single Photon Emission Computed Tomography
por: Lu, Kelly, et al.
Publicado: (2023)

Application of Cleavable Linkers to Improve Therapeutic Index of Radioligand Therapies
por: Lau, Joseph, et al.
Publicado: (2022)

Lys-urea-Aad, Lys-urea-Cmc and Lys-urea-Cms as potential pharmacophores for the design of PSMA-targeted radioligands to reduce off-target uptake in kidneys and salivary glands
por: Kuo, Hsiou-Ting, et al.
Publicado: (2023)

Peptide Radioligands in Cancer Theranostics: Agonists and Antagonists
por: Nock, Berthold A., et al.
Publicado: (2023)

Positron Emission Tomography Imaging of the Gastrin-Releasing Peptide Receptor with a Novel Bombesin Analogue
por: Lau, Joseph, et al.
Publicado: (2019)

Targeting Refractory Mantle Cell Lymphoma for Imaging and Therapy Using C-X-C Chemokine Receptor Type 4 Radioligands
por: Kwon, Daniel, et al.
Publicado: (2022)

(68)Ga-Labeled [Thz(14)]Bombesin(7–14) Analogs: Promising GRPR-Targeting Agonist PET Tracers with Low Pancreas Uptake
por: Wang, Lei, et al.
Publicado: (2023)

Synthesis and preliminary evaluation of octreotate conjugates of bioactive synthetic amatoxins for targeting somatostatin receptor (sstr2) expressing cells
por: Pryyma, Alla, et al.
Publicado: (2021)

Radioligands for Tropomyosin Receptor Kinase (Trk) Positron Emission Tomography Imaging
por: Schirrmacher, Ralf, et al.
Publicado: (2019)

Evaluation of Met-Val-Lys as a Renal Brush Border Enzyme-Cleavable Linker to Reduce Kidney Uptake of (68)Ga-Labeled DOTA-Conjugated Peptides and Peptidomimetics
por: Bendre, Shreya, et al.
Publicado: (2020)

Design, synthesis and evaluation of (18)F-labeled cationic carbonic anhydrase IX inhibitors for PET imaging
por: Zhang, Zhengxing, et al.
Publicado: (2017)

Synthesis and Evaluation of (68)Ga-Labeled (2S,4S)-4-Fluoropyrrolidine-2-Carbonitrile and (4R)-Thiazolidine-4-Carbonitrile Derivatives as Novel Fibroblast Activation Protein-Targeted PET Tracers for Cancer Imaging
por: Bendre, Shreya, et al.
Publicado: (2023)

Current status of radioligand therapy and positron-emission tomography with prostate-specific membrane antigen
por: Inubushi, Masayuki, et al.
Publicado: (2020)

Insulinoma - The incremental value of somatostatin receptor positron emission tomography
por: Arunraj, S. T., et al.
Publicado: (2017)

Synthesis and Preclinical Evaluation of Novel (68)Ga-Labeled (R)-Pyrrolidin-2-yl-boronic Acid-Based PET Tracers for Fibroblast Activation Protein-Targeted Cancer Imaging
por: Bendre, Shreya, et al.
Publicado: (2023)

Novel radioligands for imaging sigma-1 receptor in brain using positron emission tomography (PET)
por: Lan, Yu, et al.
Publicado: (2019)

Editorial: Positron Emission Tomography (PET) Imaging of Brain Biochemistry: Beyond High-Affinity Radioligands
por: Kilbourn, Michael R., et al.
Publicado: (2022)

(68)Ga-Labeled [Leu(13)ψThz(14)]Bombesin(7–14) Derivatives: Promising GRPR-Targeting PET Tracers with Low Pancreas Uptake
por: Wang, Lei, et al.
Publicado: (2022)

Novel Radioligands for Cyclic Nucleotide Phosphodiesterase Imaging with Positron Emission Tomography: An Update on Developments Since 2012
por: Schröder, Susann, et al.
Publicado: (2016)

An in vivo Pig Model for Testing Novel Positron Emission Tomography Radioligands Targeting Cerebral Protein Aggregates
por: Raval, Nakul Ravi, et al.
Publicado: (2022)

Synthesis and Evaluation of a Fluorine-18 Radioligand for Imaging Huntingtin Aggregates by Positron Emission Tomographic Imaging
por: Kaur, Tanpreet, et al.
Publicado: (2021)

Prostate-specific membrane antigen (PSMA)–ligand positron emission tomography and radioligand therapy (RLT) of prostate cancer
por: Tateishi, Ukihide
Publicado: (2020)

A Novel Radioligand Reveals Tissue Specific Pharmacological Modulation of Glucocorticoid Receptor Expression with Positron Emission Tomography
por: Huang, Yangjie, et al.
Publicado: (2020)

Development of Novel (11)C-Labeled Selective Orexin-2 Receptor Radioligands for Positron Emission Tomography Imaging
por: Rong, Jian, et al.
Publicado: (2023)

Novel agonist and antagonist radioligands for the GLP‐2 receptor. Useful tools for studies of basic GLP‐2 receptor pharmacology
por: Gadgaard, Sarina, et al.
Publicado: (2022)

[(11)C]MADAM Used as a Model for Understanding the Radiometabolism of Diphenyl Sulfide Radioligands for Positron Emission Tomography (PET)
por: Gourand, Fabienne, et al.
Publicado: (2015)

Challenges on Cyclic Nucleotide Phosphodiesterases Imaging with Positron Emission Tomography: Novel Radioligands and (Pre-)Clinical Insights since 2016
por: Schröder, Susann, et al.
Publicado: (2021)

Synthesis and Preclinical Evaluation of Three Novel (68)Ga-Labeled Bispecific PSMA/FAP-Targeting Tracers for Prostate Cancer Imaging
por: Verena, Arsyangela, et al.
Publicado: (2023)

Alpha-peptide receptor radionuclide therapy using actinium-225 labeled somatostatin receptor agonists and antagonists
por: Shi, Mengqi, et al.
Publicado: (2022)

Cardiovascular magnetic resonance imaging and clinical performance of somatostatin receptor positron emission tomography in cardiac sarcoidosis
por: Pizarro, Carmen, et al.
Publicado: (2017)

In vitro and in vivo Human Metabolism of (S)-[(18)F]Fluspidine – A Radioligand for Imaging σ(1) Receptors With Positron Emission Tomography (PET)
por: Ludwig, Friedrich-Alexander, et al.
Publicado: (2019)

One-Step (18)F-Labeling and Preclinical Evaluation of Prostate-Specific Membrane Antigen Trifluoroborate Probes for Cancer Imaging
por: Kuo, Hsiou-Ting, et al.
Publicado: (2019)

Somatostatin receptor positron emission tomography/computed tomography (PET/CT) in the evaluation of opsoclonus-myoclonus ataxia syndrome
por: Joshi, Prathamesh, et al.
Publicado: (2013)

Two Birds with One Stone: Skull Base Meningioma and Jugulotympanic Paragangliomas with Somatostatin Receptor Positron Emission Tomography
por: Treglia, Giorgio, et al.
Publicado: (2021)

Somatostatin receptor positron emission tomography/computed tomography in myocarditis following mRNA COVID-19 vaccination
por: Bollano, Entela, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_19c0cj00hq52b48l0u8764bm9p