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Radiosynthesis and evaluation of an (18)F–labeled silicon containing exendin-4 peptide as a PET probe for imaging insulinoma
BACKGROUND: Analogues of exendin-4 have been radiolabeled for imaging the glucagon-like peptide type 1 receptors (GLP-1R) which are overexpressed in insulinoma. The aim of this research was to synthesize an (18)F–labeled silicon containing exendin-4 peptide ((18)F-2) and to evaluate its in vitro and...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer International Publishing
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5824708/ https://www.ncbi.nlm.nih.gov/pubmed/29503858 http://dx.doi.org/10.1186/s41181-017-0036-6 |