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Loss of eIF4E Phosphorylation Engenders Depression-like Behaviors via Selective mRNA Translation
The MAPK/ERK (mitogen-activated protein kinases/extracellular signal-regulated kinase) pathway is a cardinal regulator of synaptic plasticity, learning, and memory in the hippocampus. One of major endpoints of this signaling cascade is the 5′ mRNA cap binding protein eIF4E (eukaryotic Initiation Fac...
Autores principales: | Amorim, Inês S., Kedia, Sonal, Kouloulia, Stella, Simbriger, Konstanze, Gantois, Ilse, Jafarnejad, Seyed Mehdi, Li, Yupeng, Kampaite, Agniete, Pooters, Tine, Romanò, Nicola, Gkogkas, Christos G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Society for Neuroscience
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5824745/ https://www.ncbi.nlm.nih.gov/pubmed/29367404 http://dx.doi.org/10.1523/JNEUROSCI.2673-17.2018 |
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