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Single-cell RNA-seq of rheumatoid arthritis synovial tissue using low-cost microfluidic instrumentation
Droplet-based single-cell RNA-seq has emerged as a powerful technique for massively parallel cellular profiling. While this approach offers the exciting promise to deconvolute cellular heterogeneity in diseased tissues, the lack of cost-effective and user-friendly instrumentation has hindered widesp...
Autores principales: | Stephenson, William, Donlin, Laura T., Butler, Andrew, Rozo, Cristina, Bracken, Bernadette, Rashidfarrokhi, Ali, Goodman, Susan M., Ivashkiv, Lionel B., Bykerk, Vivian P., Orange, Dana E., Darnell, Robert B., Swerdlow, Harold P., Satija, Rahul |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5824814/ https://www.ncbi.nlm.nih.gov/pubmed/29476078 http://dx.doi.org/10.1038/s41467-017-02659-x |
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