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Genome-wide mapping of large deletions and their population-genetic properties in dairy cattle
Large genomic deletions are potential candidate for loss-of-function, which could be lethal as homozygote. Analysing whole genome data of 175 cattle, we report 8,480 large deletions (199 bp–773 KB) with an overall false discovery rate of 8.8%; 82% of which are novel compared with deletions in the db...
Autores principales: | Mesbah-Uddin, Md, Guldbrandtsen, Bernt, Iso-Touru, Terhi, Vilkki, Johanna, De Koning, Dirk-Jan, Boichard, Didier, Lund, Mogens Sandø, Sahana, Goutam |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5824824/ https://www.ncbi.nlm.nih.gov/pubmed/28985340 http://dx.doi.org/10.1093/dnares/dsx037 |
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