Cargando…

Linear peptidomimetics as potent antagonists of Staphylococcus aureus agr quorum sensing

Staphylococcus aureus is an important pathogen causing infections in humans and animals. Increasing problems with antimicrobial resistance has prompted the development of alternative treatment strategies, including antivirulence approaches targeting virulence regulation such as the agr quorum sensin...

Descripción completa

Detalles Bibliográficos
Autores principales:	Karathanasi, Georgia, Bojer, Martin Saxtorph, Baldry, Mara, Johannessen, Bárdur Andréson, Wolff, Sanne, Greco, Ines, Kilstrup, Mogens, Hansen, Paul Robert, Ingmer, Hanne
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5824847/ https://www.ncbi.nlm.nih.gov/pubmed/29476092 http://dx.doi.org/10.1038/s41598-018-21951-4

Ejemplares similares

The agr quorum sensing system in Staphylococcus aureus cells mediates death of sub-population
por: Paulander, Wilhelm, et al.
Publicado: (2018)

Corrigendum: Cross-Talk between Staphylococcus aureus and Other Staphylococcal Species via the agr Quorum Sensing System
por: Canovas, Jaime, et al.
Publicado: (2017)

Cross-Talk between Staphylococcus aureus and Other Staphylococcal Species via the agr Quorum Sensing System
por: Canovas, Jaime, et al.
Publicado: (2016)

Corrigendum: Cross-Talk between Staphylococcus aureus and Other Staphylococcal Species via the agr Quorum Sensing System
por: Canovas, Jaime, et al.
Publicado: (2017)

Effect of Co-inhabiting Coagulase Negative Staphylococci on S. aureus agr Quorum Sensing, Host Factor Binding, and Biofilm Formation
por: Peng, Pai, et al.
Publicado: (2019)

Application of an agr-Specific Antivirulence Compound as Therapy for Staphylococcus aureus-Induced Inflammatory Skin Disease
por: Baldry, Mara, et al.
Publicado: (2018)

Identification of Four New agr Quorum Sensing-Interfering Cyclodepsipeptides from a Marine Photobacterium
por: Kjaerulff, Louise, et al.
Publicado: (2013)

Quorum Sensing-Regulated Phenol-Soluble Modulins Limit Persister Cell Populations in Staphylococcus aureus
por: Bojer, Martin S., et al.
Publicado: (2018)

Heat Resistance Mediated by a New Plasmid Encoded Clp ATPase, ClpK, as a Possible Novel Mechanism for Nosocomial Persistence of Klebsiella pneumoniae
por: Bojer, Martin Saxtorph, et al.
Publicado: (2010)

The agr Inhibitors Solonamide B and Analogues Alter Immune Responses to Staphylococccus aureus but Do Not Exhibit Adverse Effects on Immune Cell Functions
por: Baldry, Mara, et al.
Publicado: (2016)

Discovery of Potent Peptidomimetic Antagonists for Heterochromatin Protein 1 Family Proteins
por: Lamb, Kelsey N., et al.
Publicado: (2021)

Inactivation of TCA cycle enhances Staphylococcus aureus persister cell formation in stationary phase
por: Wang, Ying, et al.
Publicado: (2018)

Solonamide B Inhibits Quorum Sensing and Reduces Staphylococcus aureus Mediated Killing of Human Neutrophils
por: Nielsen, Anita, et al.
Publicado: (2014)

Chitinase Expression in Listeria monocytogenes Is Positively Regulated by the Agr System
por: Paspaliari, Dafni Katerina, et al.
Publicado: (2014)

Phenol-Soluble Modulins Modulate Persister Cell Formation in Staphylococcus aureus
por: Baldry, Mara, et al.
Publicado: (2020)

Inhibition of the ATP Synthase Eliminates the Intrinsic Resistance of Staphylococcus aureus towards Polymyxins
por: Vestergaard, Martin, et al.
Publicado: (2017)

Agr Quorum Sensing influences the Wood-Ljungdahl pathway in Clostridium autoethanogenum
por: Piatek, Pawel, et al.
Publicado: (2022)

Targeting agr- and agr-Like Quorum Sensing Systems for Development of Common Therapeutics to Treat Multiple Gram-Positive Bacterial Infections
por: Gray, Brian, et al.
Publicado: (2013)

Redox Regulation of the Quorum-sensing Transcription Factor AgrA by Coenzyme A
por: Baković, Jovana, et al.
Publicado: (2021)

Staphylococcus aureus but not Listeria monocytogenes adapt to triclosan and adaptation correlates with increased fabI expression and agr deficiency
por: Nielsen, Lene Nørby, et al.
Publicado: (2013)

Salicylic acid stabilizes Staphylococcus aureus biofilm by impairing the agr quorum-sensing system
por: Dotto, Cristian, et al.
Publicado: (2021)

Molecular assessment of accessory gene regulator (agr) quorum sensing system in biofilm forming Staphylococcus aureus and study of the effect of silver nanoparticles on agr system
por: Turkey, Ahmed Mohammed, et al.
Publicado: (2018)

Candida albicans Augments Staphylococcus aureus Virulence by Engaging the Staphylococcal agr Quorum Sensing System
por: Todd, Olivia A., et al.
Publicado: (2019)

Characterization of the genetic switch from phage ɸ13 important for Staphylococcus aureus colonization in humans
por: Kristensen, Camilla S., et al.
Publicado: (2021)

Norlichexanthone Reduces Virulence Gene Expression and Biofilm Formation in Staphylococcus aureus
por: Baldry, Mara, et al.
Publicado: (2016)

Antibiotic-Mediated Selection of Quorum-Sensing-Negative Staphylococcus aureus
por: Paulander, Wilhelm, et al.
Publicado: (2012)

Structural and Functional Basis of Potent Inhibition of Leishmanial Leucine Aminopeptidase by Peptidomimetics
por: Bhat, Saleem Yousuf, et al.
Publicado: (2021)

Fluoroquinolone resistance does not facilitate phage Φ13 integration or excision in Staphylococcus aureus
por: Leinweber, Helena, et al.
Publicado: (2023)

Evidence That VirS Is a Receptor for the Signaling Peptide of the Clostridium perfringens Agr-like Quorum Sensing System
por: Li, Jihong, et al.
Publicado: (2020)

Links between S‐adenosylmethionine and Agr‐based quorum sensing for biofilm development in Listeria monocytogenes EGD‐e
por: Lee, Yue‐Jia, et al.
Publicado: (2020)

The Lanthipeptide Synthetase-like Protein CA_C0082 Is an Effector of Agr Quorum Sensing in Clostridium acetobutylicum
por: Humphreys, Jonathan R., et al.
Publicado: (2023)

Genome-Wide Identification of Antimicrobial Intrinsic Resistance Determinants in Staphylococcus aureus
por: Vestergaard, Martin, et al.
Publicado: (2016)

Substrate Peptidomimetic Inhibitors of P. falciparum Plasmepsin X with Potent Antimalarial Activity
por: Richardson, Lachlan W., et al.
Publicado: (2022)

Macrocyclic Peptidomimetic Plasmepsin X Inhibitors with Potent In Vitro and In Vivo Antimalarial Activity
por: Kovada, Vadims, et al.
Publicado: (2023)

Selective Chemical Inhibition of agr Quorum Sensing in Staphylococcus aureus Promotes Host Defense with Minimal Impact on Resistance
por: Sully, Erin K., et al.
Publicado: (2014)

The Agr Quorum Sensing System Represses Persister Formation through Regulation of Phenol Soluble Modulins in Staphylococcus aureus
por: Xu, Tao, et al.
Publicado: (2017)

Conformational features of the Staphylococcus aureus AgrA-promoter interactions rationalize quorum-sensing triggered gene expression
por: Rajasree, Kalagiri, et al.
Publicado: (2016)

Quorum-sensing agr system of Staphylococcus aureus primes gene expression for protection from lethal oxidative stress
por: Podkowik, Magdalena, et al.
Publicado: (2023)

Modelled-Microgravity Reduces Virulence Factor Production in Staphylococcus aureus through Downregulation of agr-Dependent Quorum Sensing
por: Green, Macauley J., et al.
Publicado: (2023)

Peptidomimetics II
por: Lubell, William D
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_18p79f8ol43m6c385e5kea9je6