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Delay in seeking care for tuberculosis symptoms among adults newly diagnosed with HIV in rural Malawi

SETTING: Ten primary health clinics in rural Thyolo District, Malawi. OBJECTIVE : Tuberculosis (TB) is a common initial presentation of human immunodeficiency virus (HIV) infection. We investigated the time from TB symptom onset to HIV diagnosis to describe TB health-seeking behaviour in adults newl...

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Autores principales: Ngwira, L. G., Dowdy, D. W., Khundi, M., Barnes, G. L., Nkhoma, A., Choko, A. T., Murowa, M., Chaisson, R. E., Corbett, E. L., Fielding, K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union Against Tuberculosis and Lung Disease 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5824850/
https://www.ncbi.nlm.nih.gov/pubmed/29471905
http://dx.doi.org/10.5588/ijtld.17.0539
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author Ngwira, L. G.
Dowdy, D. W.
Khundi, M.
Barnes, G. L.
Nkhoma, A.
Choko, A. T.
Murowa, M.
Chaisson, R. E.
Corbett, E. L.
Fielding, K.
author_facet Ngwira, L. G.
Dowdy, D. W.
Khundi, M.
Barnes, G. L.
Nkhoma, A.
Choko, A. T.
Murowa, M.
Chaisson, R. E.
Corbett, E. L.
Fielding, K.
author_sort Ngwira, L. G.
collection PubMed
description SETTING: Ten primary health clinics in rural Thyolo District, Malawi. OBJECTIVE : Tuberculosis (TB) is a common initial presentation of human immunodeficiency virus (HIV) infection. We investigated the time from TB symptom onset to HIV diagnosis to describe TB health-seeking behaviour in adults newly diagnosed with HIV. DESIGN : We asked adults (⩾18 years) about the presence and duration of TB symptoms at the time of receiving a new HIV diagnosis. Associations with delayed health seeking (defined as >30 and >90 days from the onset of TB symptoms) were evaluated using multivariable logistic regression. RESULTS : TB symptoms were reported by 416 of 1265 participants (33%), of whom 36% (150/416) had been symptomatic for >30 days before HIV testing. Most participants (260/416, 63%) were below the poverty line (US$0.41 per household member per day). Patients who first sought care from informal providers had an increased odds of delay of >30 days (adjusted odds ratio [aOR] 1.6, 95%CI 0.9–2.8) or 90 days (aOR 2.0, 95%CI 1.1–3.8). CONCLUSIONS : Delayed health seeking for TB-related symptoms was common. Poverty was ubiquitous, but had no clear relationship to diagnostic delay. HIV-positive individuals who first sought care from informal providers were more likely to experience diagnostic delays for TB symptoms.
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spelling pubmed-58248502018-03-08 Delay in seeking care for tuberculosis symptoms among adults newly diagnosed with HIV in rural Malawi Ngwira, L. G. Dowdy, D. W. Khundi, M. Barnes, G. L. Nkhoma, A. Choko, A. T. Murowa, M. Chaisson, R. E. Corbett, E. L. Fielding, K. Int J Tuberc Lung Dis Original Articles SETTING: Ten primary health clinics in rural Thyolo District, Malawi. OBJECTIVE : Tuberculosis (TB) is a common initial presentation of human immunodeficiency virus (HIV) infection. We investigated the time from TB symptom onset to HIV diagnosis to describe TB health-seeking behaviour in adults newly diagnosed with HIV. DESIGN : We asked adults (⩾18 years) about the presence and duration of TB symptoms at the time of receiving a new HIV diagnosis. Associations with delayed health seeking (defined as >30 and >90 days from the onset of TB symptoms) were evaluated using multivariable logistic regression. RESULTS : TB symptoms were reported by 416 of 1265 participants (33%), of whom 36% (150/416) had been symptomatic for >30 days before HIV testing. Most participants (260/416, 63%) were below the poverty line (US$0.41 per household member per day). Patients who first sought care from informal providers had an increased odds of delay of >30 days (adjusted odds ratio [aOR] 1.6, 95%CI 0.9–2.8) or 90 days (aOR 2.0, 95%CI 1.1–3.8). CONCLUSIONS : Delayed health seeking for TB-related symptoms was common. Poverty was ubiquitous, but had no clear relationship to diagnostic delay. HIV-positive individuals who first sought care from informal providers were more likely to experience diagnostic delays for TB symptoms. International Union Against Tuberculosis and Lung Disease 2018-03 /pmc/articles/PMC5824850/ /pubmed/29471905 http://dx.doi.org/10.5588/ijtld.17.0539 Text en © 2018 Ngwira et al. This is an Open Access article distributed under the terms of the Creative Commons Attribution Licence (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution and reproduction in any medium, provided the original author and source are credited.
spellingShingle Original Articles
Ngwira, L. G.
Dowdy, D. W.
Khundi, M.
Barnes, G. L.
Nkhoma, A.
Choko, A. T.
Murowa, M.
Chaisson, R. E.
Corbett, E. L.
Fielding, K.
Delay in seeking care for tuberculosis symptoms among adults newly diagnosed with HIV in rural Malawi
title Delay in seeking care for tuberculosis symptoms among adults newly diagnosed with HIV in rural Malawi
title_full Delay in seeking care for tuberculosis symptoms among adults newly diagnosed with HIV in rural Malawi
title_fullStr Delay in seeking care for tuberculosis symptoms among adults newly diagnosed with HIV in rural Malawi
title_full_unstemmed Delay in seeking care for tuberculosis symptoms among adults newly diagnosed with HIV in rural Malawi
title_short Delay in seeking care for tuberculosis symptoms among adults newly diagnosed with HIV in rural Malawi
title_sort delay in seeking care for tuberculosis symptoms among adults newly diagnosed with hiv in rural malawi
topic Original Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5824850/
https://www.ncbi.nlm.nih.gov/pubmed/29471905
http://dx.doi.org/10.5588/ijtld.17.0539
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