Functionally distinct disease-associated fibroblast subsets in rheumatoid arthritis

Fibroblasts regulate tissue homeostasis, coordinate inflammatory responses, and mediate tissue damage. In rheumatoid arthritis (RA), synovial fibroblasts maintain chronic inflammation which leads to joint destruction. Little is known about fibroblast heterogeneity or if aberrations in fibroblast sub...

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Detalles Bibliográficos
Autores principales: Mizoguchi, Fumitaka, Slowikowski, Kamil, Wei, Kevin, Marshall, Jennifer L., Rao, Deepak A., Chang, Sook Kyung, Nguyen, Hung N., Noss, Erika H., Turner, Jason D., Earp, Brandon E., Blazar, Philip E., Wright, John, Simmons, Barry P., Donlin, Laura T., Kalliolias, George D., Goodman, Susan M., Bykerk, Vivian P., Ivashkiv, Lionel B., Lederer, James A., Hacohen, Nir, Nigrovic, Peter A., Filer, Andrew, Buckley, Christopher D., Raychaudhuri, Soumya, Brenner, Michael B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5824882/
https://www.ncbi.nlm.nih.gov/pubmed/29476097
http://dx.doi.org/10.1038/s41467-018-02892-y

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