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The role of sortilin in the “Glut4 Pathway”.
Sorting receptor, sortilin, is highly expressed in metabolically active tissues, such as brain, liver, skeletal muscle, and fat. Specifically in adipocytes, sortilin plays an important role in the “Glut4 pathway” by sorting the insulin-responsive glucose transporter, Glut4, in early endosomes and tr...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Taylor & Francis
2017
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5824963/ http://dx.doi.org/10.1080/19420889.2017.1393592 |
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author | Kandror, Konstantin V. |
author_facet | Kandror, Konstantin V. |
author_sort | Kandror, Konstantin V. |
collection | PubMed |
description | Sorting receptor, sortilin, is highly expressed in metabolically active tissues, such as brain, liver, skeletal muscle, and fat. Specifically in adipocytes, sortilin plays an important role in the “Glut4 pathway” by sorting the insulin-responsive glucose transporter, Glut4, in early endosomes and trans-Golgi network and re-routing the transporter from degradation to the recycling pathway. |
format | Online Article Text |
id | pubmed-5824963 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Taylor & Francis |
record_format | MEDLINE/PubMed |
spelling | pubmed-58249632018-03-01 The role of sortilin in the “Glut4 Pathway”. Kandror, Konstantin V. Commun Integr Biol Article Addendum Sorting receptor, sortilin, is highly expressed in metabolically active tissues, such as brain, liver, skeletal muscle, and fat. Specifically in adipocytes, sortilin plays an important role in the “Glut4 pathway” by sorting the insulin-responsive glucose transporter, Glut4, in early endosomes and trans-Golgi network and re-routing the transporter from degradation to the recycling pathway. Taylor & Francis 2017-12-14 /pmc/articles/PMC5824963/ http://dx.doi.org/10.1080/19420889.2017.1393592 Text en © 2017 The Author(s). Published with license by Taylor & Francis http://creativecommons.org/licenses/by/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Article Addendum Kandror, Konstantin V. The role of sortilin in the “Glut4 Pathway”. |
title | The role of sortilin in the “Glut4 Pathway”. |
title_full | The role of sortilin in the “Glut4 Pathway”. |
title_fullStr | The role of sortilin in the “Glut4 Pathway”. |
title_full_unstemmed | The role of sortilin in the “Glut4 Pathway”. |
title_short | The role of sortilin in the “Glut4 Pathway”. |
title_sort | role of sortilin in the “glut4 pathway”. |
topic | Article Addendum |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5824963/ http://dx.doi.org/10.1080/19420889.2017.1393592 |
work_keys_str_mv | AT kandrorkonstantinv theroleofsortilinintheglut4pathway AT kandrorkonstantinv roleofsortilinintheglut4pathway |