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The role of sortilin in the “Glut4 Pathway”.

Sorting receptor, sortilin, is highly expressed in metabolically active tissues, such as brain, liver, skeletal muscle, and fat. Specifically in adipocytes, sortilin plays an important role in the “Glut4 pathway” by sorting the insulin-responsive glucose transporter, Glut4, in early endosomes and tr...

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Detalles Bibliográficos
Autor principal: Kandror, Konstantin V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5824963/
http://dx.doi.org/10.1080/19420889.2017.1393592
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author Kandror, Konstantin V.
author_facet Kandror, Konstantin V.
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description Sorting receptor, sortilin, is highly expressed in metabolically active tissues, such as brain, liver, skeletal muscle, and fat. Specifically in adipocytes, sortilin plays an important role in the “Glut4 pathway” by sorting the insulin-responsive glucose transporter, Glut4, in early endosomes and trans-Golgi network and re-routing the transporter from degradation to the recycling pathway.
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spelling pubmed-58249632018-03-01 The role of sortilin in the “Glut4 Pathway”. Kandror, Konstantin V. Commun Integr Biol Article Addendum Sorting receptor, sortilin, is highly expressed in metabolically active tissues, such as brain, liver, skeletal muscle, and fat. Specifically in adipocytes, sortilin plays an important role in the “Glut4 pathway” by sorting the insulin-responsive glucose transporter, Glut4, in early endosomes and trans-Golgi network and re-routing the transporter from degradation to the recycling pathway. Taylor & Francis 2017-12-14 /pmc/articles/PMC5824963/ http://dx.doi.org/10.1080/19420889.2017.1393592 Text en © 2017 The Author(s). Published with license by Taylor & Francis http://creativecommons.org/licenses/by/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Article Addendum
Kandror, Konstantin V.
The role of sortilin in the “Glut4 Pathway”.
title The role of sortilin in the “Glut4 Pathway”.
title_full The role of sortilin in the “Glut4 Pathway”.
title_fullStr The role of sortilin in the “Glut4 Pathway”.
title_full_unstemmed The role of sortilin in the “Glut4 Pathway”.
title_short The role of sortilin in the “Glut4 Pathway”.
title_sort role of sortilin in the “glut4 pathway”.
topic Article Addendum
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5824963/
http://dx.doi.org/10.1080/19420889.2017.1393592
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