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CR6 interacting factor 1 deficiency promotes endothelial inflammation by SIRT1 downregulation

AIMS: CR6 interacting factor 1 (CRIF1) deficiency impairs mitochondrial oxidative phosphorylation complexes, contributing to increased mitochondrial and cellular reactive oxygen species (ROS) production. CRIF1 downregulation has also been revealed to decrease sirtuin 1 (SIRT1) expression and impair...

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Detalles Bibliográficos
Autores principales:	Piao, Shuyu, Lee, Jun Wan, Nagar, Harsha, Jung, Saet-byel, Choi, Sujeong, Kim, Seonhee, Lee, Ikjun, Kim, Sung-min, Shin, Nara, Lee, Yu Ran, Lee, Sang Do, Park, Jin Bong, Irani, Kaikobad, Won, Minho, Hur, Gang Min, Jeon, Byeong Hwa, Kim, Dong Woon, Kim, Cuk-Seong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5825004/ https://www.ncbi.nlm.nih.gov/pubmed/29474366 http://dx.doi.org/10.1371/journal.pone.0192693

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